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基于临床-放射-病理相关性解读重症冠状病毒病19型肺炎（COVID-19）的肺血管并发症

Demystifying pulmonary vascular complications in severe coronavirus disease-19 pneumonia (COVID-19) in the light of clinico-radiologic-pathologic correlation.

作者信息

Parry Arshed Hussain, Wani Abdul Haseeb, Yaseen Mudasira, Dar Mohd Iqbal

机构信息

Senior Resident, Department of Radiodiagnosis, Sher-i-Kashmir Institute of Medical Sciences, Srinagar, Jammu & Kashmir, India.

Consultant, Department of Radiodiagnosis, Government Medical College, Srinagar, Jammu & Kashmir, India.

出版信息

Thromb Res. 2020 Dec;196:559-560. doi: 10.1016/j.thromres.2020.06.043. Epub 2020 Jun 27.

DOI:10.1016/j.thromres.2020.06.043
PMID:32620455
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7319924/
Abstract

• Small pulmonary vessel changes are a unique imaging feature of COVID-19 pneumonia. • Autopsy studies reveal a very high incidence of peripheral pulmonary thrombosis. • Risk of thrombosis is high in severe COVID-19 despite anticoagulation. • Mounting evidence suggests immunothrombosis as a contributory cause of thrombosis. • Combined inflammation reduction and anticoagulation seems to be a rational therapeutic protocol.

摘要

• 小肺血管改变是新冠肺炎肺炎的独特影像学特征。

• 尸检研究显示外周肺血栓形成的发生率非常高。

• 尽管进行了抗凝治疗，但重症新冠肺炎患者的血栓形成风险仍然很高。

• 越来越多的证据表明免疫血栓形成是血栓形成的一个促成因素。

• 联合减轻炎症和抗凝似乎是一种合理的治疗方案。

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Thromb Res. 2020 Sep;193:86-89. doi: 10.1016/j.thromres.2020.06.010. Epub 2020 Jun 6.
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Thromb Res. 2020 Sep;193:1-4. doi: 10.1016/j.thromres.2020.05.049. Epub 2020 May 29.
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