Bartolini A, Gasparetto B, Bacigalupo F, Ruffinengo U, Amore R, Loeb C
Institute of Clinical Neurology, University of Genoa, Italy.
Eur Neurol. 1988;28(4):232-5. doi: 10.1159/000116273.
94 subjects, 64 with cerebral ischemia of varying severity and outcome, and 30 controls were studied with technetium-99m hexamethyl propylenamino oxime single photon emission computed tomography in order to evaluate the suitability of this technique in the assessment of cerebral ischemia. Decreased uptake corresponding to the side of clinical symptomatology and/or to CT lesion was found in 93% of the patients with complete stroke and in 28% of the patients with transient ischemic attack. This procedure can be a useful tool in the routine examination of ischemic patients, although the mechanism underlying brain uptake is far from being completely understood and the possible quantitative evaluation of regional cerebral blood flow is worthy of further assessment.
对94名受试者进行了研究，其中64名患有不同严重程度和转归的脑缺血患者，30名作为对照，采用锝-99m六甲基丙烯胺肟单光子发射计算机断层扫描，以评估该技术在脑缺血评估中的适用性。在完全性卒中患者中，93%发现与临床症状侧和/或CT病变侧相对应的摄取减少；在短暂性脑缺血发作患者中，28%发现有此情况。尽管脑摄取的潜在机制远未完全明了，且区域脑血流量的可能定量评估值得进一步评估，但该检查方法在缺血性患者的常规检查中可能是一种有用的工具。
