Department of Oral Pathology and Microbiology, Faculty of Dental Sciences, M.S. Ramaiah University of Applied Sciences, Bangalore, India.
Department of Pathology, Jagadguru Jayadeva Murugarajendra Medical College, Davanagere, India.
Dis Mon. 2020 Dec;66(12):101035. doi: 10.1016/j.disamonth.2020.101035. Epub 2020 Jul 1.
This review has addressed the issues faced by a diagnostic pathologist during routine assessment of haematoxylin and eosin stained incisional biopsies from oral squamous cell carcinoma patients. Herein, the pragmatic means undertaken, has highlighted routinely faced problems & encounters determined at various levels as clinical, laboratory and diagnostic pitfalls, when possible, tips offered towards procedures and guidance. Also, dealt with subtypes of oral squamous cell carcinoma, differential diagnosis, and relevant prognostic indicators that can navigate the surgeon to take quick decisions. It speaks of the journey of biopsied material from the clinician to the laboratory until the generation of the final report. Although histopathological evaluation is a confirmatory tool for any clinically suspected lesion it mandates the co-operation of faculty from varied disciplines. The onus lies on a pathologist to establish standard protocols to oversee, audit the laboratory operating procedures from time and again. Technical errors and faults at the office desk doesn't come under the purview of this review.
本文针对诊断病理学家在常规评估口腔鳞状细胞癌患者的苏木精和伊红染色切取活检时所面临的问题进行了综述。文中介绍了在临床、实验室和诊断陷阱等各个层面上经常遇到的问题和遇到的问题，并就可能的情况提供了一些针对操作程序和指导的建议。此外，还涉及了口腔鳞状细胞癌的亚型、鉴别诊断以及相关的预后指标，这些内容可以为外科医生提供快速决策的依据。本文还讲述了从临床医生到实验室，直到生成最终报告的活检材料的处理过程。尽管组织病理学评估是对任何临床疑似病变的确认工具，但它需要来自不同学科的教职员工的合作。病理学家有责任建立标准协议，以定期监督和审查实验室的操作程序。本文不涉及办公室桌面的技术错误和故障。
