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Beltherm MP/ML(内切-1,4-β-木聚糖酶)作为育肥鸡、产蛋鸡、育肥火鸡、种用火鸡、种用火鸡及小型家禽品种饲料添加剂的安全性和有效性。

Safety and efficacy of Beltherm MP/ML (endo-1,4-beta-xylanase) as a feed additive for chickens for fattening, chickens reared for laying, turkeys for fattening, turkeys reared for breeding, turkeys for breeding purposes and minor poultry species.

作者信息

Rychen Guido, Aquilina Gabriele, Azimonti Giovanna, Bampidis Vasileios, Bastos Maria de Lourdes, Bories Georges, Chesson Andrew, Flachowsky Gerhard, Gropp Jürgen, Kolar Boris, Kouba Maryline, López Puente Secundino, López-Alonso Marta, Mantovani Alberto, Mayo Baltasar, Ramos Fernando, Saarela Maria, Villa Roberto Edoardo, Wallace Robert John, Wester Pieter, Dierick Noël Albert, Brantom Paul, Glandorf Boet, Herman Lieve, Kärenlampi Sirpa, Aguilera Jaime, Anguita Montserrat, Cocconcelli Pier Sandro

出版信息

EFSA J. 2017 Jul 28;15(7):e04941. doi: 10.2903/j.efsa.2017.4941. eCollection 2017 Jul.

Abstract

Beltherm MP/ML is a feed additive that contains endo-1,4-beta-xylanase to be used as a zootechnical additive in poultry species. The production strain of the xylanase is a genetically modified strain of . This species is considered by EFSA to qualify for the qualified presumption of safety (QPS) approach to safety assessment. The strain was unequivocally identified and qualifications were met. The genetic modification along with the results on the investigations regarding the presence? of the production strain and its DNA in the product were evaluated by the EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) and raised no safety concerns. The FEEDAP Panel also concluded that the additive is safe for chickens and turkeys for fattening, chickens reared for laying, turkeys reared for breeding, turkeys for breeding purposes and minor poultry species at 100 ADXU/kg feed with a wide margin of safety. The Panel also concluded that no toxicological concerns for the consumer would arise from the use of Beltherm as a feed additive. The additive is considered a potential respiratory sensitiser for users. The Panel concluded that the use of the product as a feed additive raises no safety concerns for the environment. The additive has the potential to improve the performance of chickens for fattening, chickens reared for laying and minor growing poultry species at the dose of 100 ADXU/kg feed. The Panel could not conclude on the efficacy of the product in turkeys for fattening or reared for breeding or in turkeys for breeding purposes.

摘要

倍特热MP/ML是一种饲料添加剂,含有内切-1,4-β-木聚糖酶,用作家禽的动物技术添加剂。木聚糖酶的生产菌株是一种基因改造菌株。欧洲食品安全局(EFSA)认为该菌株符合安全评估的合格假定安全(QPS)方法。该菌株已得到明确鉴定且符合相关要求。动物饲料添加剂和产品或物质专家委员会(FEEDAP)对该基因改造以及关于产品中生产菌株及其DNA存在情况的调查结果进行了评估,未发现安全问题。FEEDAP专家委员会还得出结论,对于育肥鸡、产蛋鸡、种用火鸡、种用火鸡以及小型家禽品种,该添加剂在100 ADXU/kg饲料的添加量下是安全的,且具有较大的安全边际。专家委员会还得出结论,将倍特热用作饲料添加剂不会对消费者产生毒理学方面的担忧。该添加剂被认为对使用者有潜在的呼吸道致敏性。专家委员会得出结论,将该产品用作饲料添加剂对环境不会产生安全问题。在100 ADXU/kg饲料的添加量下,该添加剂有潜力提高育肥鸡、产蛋鸡和小型生长家禽品种的生产性能。专家委员会无法就该产品对育肥火鸡、种用火鸡或种用火鸡的功效得出结论。

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