Rychen Guido, Aquilina Gabriele, Azimonti Giovanna, Bampidis Vasileios, Bastos Maria de Lourdes, Bories Georges, Chesson Andrew, Cocconcelli Pier Sandro, Flachowsky Gerhard, Gropp Jürgen, Kolar Boris, Kouba Maryline, López Puente Secundino, López-Alonso Marta, Mantovani Alberto, Mayo Baltasar, Ramos Fernando, Saarela Maria, Villa Roberto Edoardo, Wallace Robert John, Wester Pieter, Brantom Paul, Dierick Noël Albert, Aguilera Jaime, Anguita Montserrat
EFSA J. 2017 Aug 2;15(8):e04943. doi: 10.2903/j.efsa.2017.4943. eCollection 2017 Aug.
FRA Octazyme C Dry is a product that presents α-galactosidase, α-amylase, endo-1,3(4)-β-glucanase, endo-1,4-β-glucanase, mannan-endo-1,4-β-mannosidase, pectinase, protease and endo-1,4-β-xylanase. It is intended to be used as a zootechnical additive for chickens for fattening and weaned piglets. The enzymes present in the additive are obtained from six different fermentation processes with four different microorganisms, , , and . In the tolerance and efficacy trials done in the target species, major limitations on the analysed enzyme activities in the feed were identified. These limitations did not permit the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) to conclude on the safety and efficacy of FRA Octazyme C Dry for the target species. The Panel concluded that the additive raises no concerns for the consumers of food products obtained from animals fed with the additive. No specific data were submitted to address the safety for the user, in the absence of such data the FEEDAP Panel could not conclude on the potential of the additive to be irritant to the skin and eyes or on its skin sensitising properties. Owing to the nature of the active substances, the additive should be considered a potential respiratory sensitiser. The use of FRA Octazyme C Dry as a feed additive poses no risks to the environment.
FRA Octazyme C Dry是一种含有α-半乳糖苷酶、α-淀粉酶、内切-1,3(4)-β-葡聚糖酶、内切-1,4-β-葡聚糖酶、甘露聚糖内切-1,4-β-甘露糖苷酶、果胶酶、蛋白酶和内切-1,4-β-木聚糖酶的产品。它旨在用作育肥鸡和断奶仔猪的动物技术添加剂。该添加剂中的酶是通过四种不同微生物，即 、 、 和 的六种不同发酵过程获得的。在针对目标物种进行的耐受性和功效试验中，确定了饲料中分析的酶活性存在重大限制。这些限制使得动物饲料添加剂及产品或物质专家委员会（FEEDAP）无法就FRA Octazyme C Dry对目标物种的安全性和功效得出结论。专家委员会得出结论，该添加剂不会引起食用添加该添加剂的动物所产食品的消费者的担忧。未提交具体数据以解决对使用者的安全性问题，由于缺乏此类数据，FEEDAP专家委员会无法就该添加剂对皮肤和眼睛的刺激性潜力或其皮肤致敏特性得出结论。由于活性物质的性质，该添加剂应被视为潜在的呼吸道致敏剂。将FRA Octazyme C Dry用作饲料添加剂对环境没有风险。
