• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

关于在活性物质甲基毒死蜱农药同行评审背景下人类健康评估现有结果的更新声明。

Updated statement on the available outcomes of the human health assessment in the context of the pesticides peer review of the active substance chlorpyrifos-methyl.

出版信息

EFSA J. 2019 Nov 26;17(11):e05908. doi: 10.2903/j.efsa.2019.5908. eCollection 2019 Nov.

DOI:10.2903/j.efsa.2019.5908
PMID:32626191
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7008899/
Abstract

In July 2019, the European Commission asked EFSA to provide a statement on the available outcomes of the human health assessment in the context of the pesticides peer review for the renewal of approval of the active substance chlorpyrifos-methyl conducted in accordance with Commission Implementing Regulation (EC) No 844/2012. Accordingly, EFSA delivered a statement to the Commission providing a summary of the main findings of the assessment related to human health following the pesticides peer review expert discussions in mammalian toxicology held between 1 and 5 April 2019, as well as EFSA's additional considerations, including whether the active substance can be expected to meet the approval criteria applicable to human health as laid down in Article 4 of Regulation (EC) No 1107/2009. A follow-up mandate was received to update the statement issued on 31 July 2019 with the outcome of the expert meeting in mammalian toxicology held on 5 September 2019 during which chlorpyrifos-methyl was rediscussed. The concerns identified in the previous statement are maintained.

摘要

2019年7月,欧盟委员会要求欧洲食品安全局就按照委员会实施条例(EC)No 844/2012对活性物质甲基毒死蜱重新批准进行的农药同行评审中人类健康评估的现有结果发表声明。据此,欧洲食品安全局向委员会提交了一份声明,概述了2019年4月1日至5日举行的哺乳动物毒理学农药同行评审专家讨论后与人类健康相关的评估主要结果,以及欧洲食品安全局的其他考虑因素,包括该活性物质是否有望符合(EC)No 1107/2009号条例第4条规定的适用于人类健康的批准标准。收到了一项后续任务授权,用2019年9月5日举行的哺乳动物毒理学专家会议结果更新2019年7月31日发布的声明,该会议期间重新讨论了甲基毒死蜱。先前声明中确定的问题仍然存在。

相似文献

1
Updated statement on the available outcomes of the human health assessment in the context of the pesticides peer review of the active substance chlorpyrifos-methyl.关于在活性物质甲基毒死蜱农药同行评审背景下人类健康评估现有结果的更新声明。
EFSA J. 2019 Nov 26;17(11):e05908. doi: 10.2903/j.efsa.2019.5908. eCollection 2019 Nov.
2
Statement on the available outcomes of the human health assessment in the context of the pesticides peer review of the active substance chlorpyrifos-methyl.关于在活性物质甲基毒死蜱农药同行评审背景下人类健康评估现有结果的声明
EFSA J. 2019 Aug 28;17(8):e05810. doi: 10.2903/j.efsa.2019.5810. eCollection 2019 Aug.
3
Statement on the available outcomes of the human health assessment in the context of the pesticides peer review of the active substance chlorpyrifos.关于在活性物质毒死蜱农药同行评审背景下人类健康评估现有结果的声明。
EFSA J. 2019 Aug 28;17(8):e05809. doi: 10.2903/j.efsa.2019.5809. eCollection 2019 Aug.
4
Statement concerning the assessment of environmental fate and behaviour and ecotoxicology in the context of the pesticides peer review of the active substance dimoxystrobin.关于在活性物质嘧菌酯农药同行评审背景下对环境归宿与行为及生态毒理学评估的声明
EFSA J. 2022 Nov 15;20(11):e07634. doi: 10.2903/j.efsa.2022.7634. eCollection 2022 Nov.
5
Statement concerning the testing strategy and timelines proposed by the applicant for the assessment of the endocrine disruption properties of acibenzolar-S-methyl in the context of the review of the approval of the active substance.关于申请人在活性物质批准审查背景下提出的用于评估烯丙苯噻唑甲基内分泌干扰特性的测试策略和时间表的声明。
EFSA J. 2023 Apr 20;21(4):e07968. doi: 10.2903/j.efsa.2023.7968. eCollection 2023 Apr.
6
Updated peer review concerning the risk to mammals and bees for the active substance indoxacarb.关于活性成分茚虫威对哺乳动物和蜜蜂风险的最新同行评审。
EFSA J. 2019 Oct 29;17(10):e05866. doi: 10.2903/j.efsa.2019.5866. eCollection 2019 Oct.
7
Statement concerning the review of the approval of the active substance pirimicarb.关于对活性物质抗蚜威批准情况审查的声明。
EFSA J. 2023 Feb 16;21(2):e07807. doi: 10.2903/j.efsa.2023.7807. eCollection 2023 Feb.
8
Statement on the refined environmental risk assessment and impact of the new classification for captan.关于克菌丹新分类的精细环境风险评估及影响的声明
EFSA J. 2024 Feb 23;22(2):e8576. doi: 10.2903/j.efsa.2024.8576. eCollection 2024 Feb.
9
Peer review of the pesticide risk assessment for bees for the active substance clothianidin considering the uses as seed treatments and granules.考虑到噻虫胺作为种子处理剂和颗粒剂的用途,对活性物质噻虫胺进行蜜蜂农药风险评估的同行评审。
EFSA J. 2018 Feb 28;16(2):e05177. doi: 10.2903/j.efsa.2018.5177. eCollection 2018 Feb.
10
Peer review of the pesticide risk assessment for bees for the active substance imidacloprid considering the uses as seed treatments and granules.考虑吡虫啉作为种子处理剂和颗粒剂的用途,对其蜜蜂农药风险评估进行同行评审。
EFSA J. 2018 Feb 28;16(2):e05178. doi: 10.2903/j.efsa.2018.5178. eCollection 2018 Feb.

引用本文的文献

1
Peer review of the pesticide risk assessment of the active substance triclopyr (variant triclopyr-butotyl).活性物质三氯吡氧乙酸(三氯吡氧乙酸丁氧基乙酯变体)农药风险评估的同行评审
EFSA J. 2024 Aug 12;22(8):e8177. doi: 10.2903/j.efsa.2024.8177. eCollection 2024 Aug.
2
Assessment of exposure to pesticides: residues in 24 h duplicate diets versus their metabolites in 24 h urine using suspect screening and target analysis.暴露评估:24 小时双份饮食残留与 24 小时尿液代谢物的疑似筛查和目标分析。
Anal Bioanal Chem. 2024 Jan;416(3):635-650. doi: 10.1007/s00216-023-04918-x. Epub 2023 Sep 22.
3
Challenges in the Application of Circular Economy Models to Agricultural By-Products: Pesticides in Spain as a Case Study.将循环经济模式应用于农业副产品的挑战:以西班牙的农药为例进行研究
Foods. 2023 Aug 15;12(16):3054. doi: 10.3390/foods12163054.
4
Modification of the existing maximum residue levels for triclopyr in animal commodities.调整动物源性产品中三氯吡氧乙酸的现有最大残留限量。
EFSA J. 2023 May 5;21(5):e08007. doi: 10.2903/j.efsa.2023.8007. eCollection 2023 May.
5
Modification of the existing maximum residue levels for triclopyr in oranges, lemons and mandarins.修改橙子、柠檬和柑橘中三氯吡氧乙酸的现有最大残留限量。
EFSA J. 2022 Aug 22;20(8):e07545. doi: 10.2903/j.efsa.2022.7545. eCollection 2022 Aug.
6
Improving the Risk Assessment of Pesticides through the Integration of Human Biomonitoring and Food Monitoring Data: A Case Study for Chlorpyrifos.通过整合人体生物监测和食品监测数据改进农药风险评估:毒死蜱案例研究
Toxics. 2022 Jun 9;10(6):313. doi: 10.3390/toxics10060313.
7
Scientific support for preparing an EU position for the 52nd Session of the Codex Committee on Pesticide Residues (CCPR).为农药残留法典委员会(CCPR)第52届会议制定欧盟立场提供科学支持。
EFSA J. 2021 Aug 17;19(8):e06766. doi: 10.2903/j.efsa.2021.6766. eCollection 2021 Aug.

本文引用的文献

1
Statement on the available outcomes of the human health assessment in the context of the pesticides peer review of the active substance chlorpyrifos-methyl.关于在活性物质甲基毒死蜱农药同行评审背景下人类健康评估现有结果的声明
EFSA J. 2019 Aug 28;17(8):e05810. doi: 10.2903/j.efsa.2019.5810. eCollection 2019 Aug.
2
Guidance for the identification of endocrine disruptors in the context of Regulations (EU) No 528/2012 and (EC) No 1107/2009.关于在(欧盟)第528/2012号法规和(欧盟)第1107/2009号法规背景下识别内分泌干扰物的指南。
EFSA J. 2018 Jun 7;16(6):e05311. doi: 10.2903/j.efsa.2018.5311. eCollection 2018 Jun.
3
Enzymatic degradation of extracellular DNA exposed to chlorpyrifos and chlorpyrifos-methyl in an aqueous system.在水体系中,暴露于毒死蜱和毒死蜱-甲基的细胞外 DNA 的酶促降解。
Environ Int. 2019 Nov;132:105087. doi: 10.1016/j.envint.2019.105087. Epub 2019 Aug 17.
4
Insecticide toxic effects and blood biochemical alterations in occupationally exposed individuals in Punjab, Pakistan.巴基斯坦旁遮普职业暴露人群的杀虫剂毒性作用和血液生化改变。
Sci Total Environ. 2019 Mar 10;655:102-111. doi: 10.1016/j.scitotenv.2018.11.175. Epub 2018 Nov 13.
5
Safety of Safety Evaluation of Pesticides: developmental neurotoxicity of chlorpyrifos and chlorpyrifos-methyl.农药安全性评价的安全性:毒死蜱和毒死蜱甲基的发育神经毒性。
Environ Health. 2018 Nov 16;17(1):77. doi: 10.1186/s12940-018-0421-y.
6
Prenatal naled and chlorpyrifos exposure is associated with deficits in infant motor function in a cohort of Chinese infants.在中国一组婴儿队列中,产前暴露于敌敌畏和毒死蜱与婴儿运动功能缺陷有关。
Environ Int. 2017 Sep;106:248-256. doi: 10.1016/j.envint.2017.05.015. Epub 2017 Jun 8.
7
Effect on the H19 gene methylation of sperm and organs of offspring after chlorpyrifos-methyl exposure during organogenesis period.甲基毒死蜱在器官发生期暴露后对后代精子和器官H19基因甲基化的影响。
Environ Toxicol. 2015 Dec;30(12):1355-63. doi: 10.1002/tox.21923. Epub 2015 Mar 17.
8
Exposure of pregnant mice to chlorpyrifos-methyl alters embryonic H19 gene methylation patterns.怀孕老鼠接触毒死蜱会改变胚胎 H19 基因的甲基化模式。
Environ Toxicol. 2014 Aug;29(8):926-35. doi: 10.1002/tox.21820. Epub 2012 Nov 2.
9
Detection of DNA damage by using hairpin molecular beacon probes and graphene oxide.利用发夹分子信标探针和氧化石墨烯检测 DNA 损伤。
Talanta. 2012 Sep 15;99:625-30. doi: 10.1016/j.talanta.2012.06.049. Epub 2012 Jun 26.
10
Brain anomalies in children exposed prenatally to a common organophosphate pesticide.儿童在产前暴露于常见有机磷酸酯类杀虫剂会出现脑部异常。
Proc Natl Acad Sci U S A. 2012 May 15;109(20):7871-6. doi: 10.1073/pnas.1203396109. Epub 2012 Apr 30.