Department of Cardiovascular & Thoracic Sciences, Institute of Cardiology, Catholic University of The Sacred Heart, Rome, Italy.
Department of Cardiovascular Sciences, Fondazione Policlinico Universitario A. Gemelli, IRCCS, Rome, Italy.
Future Cardiol. 2021 Jan;17(1):149-154. doi: 10.2217/fca-2020-0052. Epub 2020 Jul 6.
Myocardial infarction with non-obstructive coronary artery (MINOCA) disease represents a heterogeneous clinical conundrum accounting for about 6% of all acute myocardial infarction (MI) cases. Initially believed to be a benign condition, is now becoming clear that MINOCA is associated with a non-negligible risk of mortality, rehospitalization, disability and angina burden at follow-up, with high socioeconomic costs. To date, there are no prospective clinical trials in this population and cannot be assumed that benefits observed in patients suffering from MI with obstructive coronary artery disease may successfully translate to this syndrome. Herein, we comment on the importance of the multimodality assessment to properly identify and treat the specific causes of MINOCA, in order to improve prognosis and the quality of life in these patients.
非阻塞性冠状动脉心肌梗死（MINOCA）疾病代表了一种异质性的临床难题，约占所有急性心肌梗死（MI）病例的 6%。最初被认为是一种良性疾病，但现在越来越清楚的是，MINOCA 与死亡率、再住院率、残疾和随访时的心绞痛负担相关，具有较高的社会经济成本。迄今为止，该人群中尚无前瞻性临床试验，不能假设在患有阻塞性冠状动脉疾病的 MI 患者中观察到的益处可以成功转化为这种综合征。在此，我们评论了多模态评估的重要性，以便正确识别和治疗 MINOCA 的特定病因，从而改善这些患者的预后和生活质量。
