Akaike N, Oyama Y, Tokutomi N
Department of Physiology, Faculty of Medicine, Kyushu University, Fukuoka, Japan.
Neurosci Res. 1988 Aug;5(6):557-62. doi: 10.1016/0168-0102(88)90042-9.
In isolated and internally perfused frog sensory neurons, muscimol-, pentobarbital- and alpha-chloralose-induced Cl- currents were suppressed by voltage-dependent Ca2+ currents. The amount of chloride currents inhibited by Ca2+ influx developed in a hyperbolic manner as a function of Ca2+ influx. The increase in intracellular Ca2+ concentration also suppressed the currents carried by monovalent anions, such as Br-, I-, NO3- and HCOO-.
在分离并进行内部灌注的青蛙感觉神经元中,蝇蕈醇、戊巴比妥和α-氯醛糖诱导的氯离子电流受到电压依赖性钙电流的抑制。随着钙内流增加,被钙内流抑制的氯离子电流数量呈双曲线方式增加。细胞内钙离子浓度的升高也抑制了一价阴离子(如溴离子、碘离子、硝酸根离子和甲酸根离子)所携带的电流。