Levine Cancer Institute of Atrium Health, Charlotte, North Carolina.
Carolinas Medical Center of Atrium Health, Charlotte, North Carolina.
Clin Adv Hematol Oncol. 2020 May;18(5):280-288.
Pancreatic adenocarcinoma is one of the most lethal cancers in oncology. Pancreatic cancer is the third most common cause of cancer-related mortality in the United States. As the years have progressed, the importance of a multidisciplinary and multimodal approach to pancreatic cancer care has been recognized and is now recommended in all major society guidelines. A subset of pancreatic cancer, borderline resectable pancreatic cancer (BRPC), has emerged as a distinct clinical entity for which specialized treatment plans are now being developed. The medical oncologist, surgical oncologist, and radiation oncologist must work jointly to help deliver the best clinical outcome for the patient with pancreatic cancer. In this discussion, we describe the current state of surgical, locoregional therapies and systemic therapy in BRPC.
胰腺腺癌是肿瘤学中最致命的癌症之一。在美国，胰腺癌是癌症相关死亡的第三大常见原因。随着时间的推移，人们已经认识到多学科和多模式方法治疗胰腺癌的重要性，现在所有主要的协会指南都推荐这种方法。胰腺癌症的一个亚组，边界可切除性胰腺癌症（BRPC），已经成为一个独特的临床实体，现在正在为其制定专门的治疗计划。肿瘤内科医生、外科肿瘤医生和放射肿瘤医生必须共同努力，为胰腺癌患者提供最佳的临床治疗效果。在本次讨论中，我们描述了 BRPC 中当前的手术、局部区域治疗和系统治疗状况。
