Consultant Cardiologist, Department of Cardiology, Rawalpindi Institute of Cardiology, Pakistan.
Resident Physician, Department of Cardiology, Rawalpindi Institute of Cardiology, Pakistan.
Scott Med J. 2021 Feb;66(1):34-39. doi: 10.1177/0036933020941260. Epub 2020 Jul 6.
Despite restoration of blood flow, subtle microvascular obstruction can occur. This obstruction can be graded using myocardial blush grade. We aimed to investigate the role of myocardial blush grade in ejection fraction and adverse outcomes, after percutaneous intervention.
A prospective, observational study was conducted at our institute with a calculated sample size. Variables such as age, gender, and ejection fraction were noted before the intervention. The patients were followed for 3 months to determine the outcomes. The data was analyzed using IBM SPSS software version 26.0. P-value of less than 0.05 was considered significant for the statistical tests.
There were 74 male and 36 female participants in the study. The mean age was 52.20 ± 10.02 years. The most common adverse outcome was heart failure (18%). There was a significant Pearson's correlation between myocardial blush grade and improvement in ejection fraction (p < 0.05). Improvement in myocardial blush grade was significantly related to a decrease in adverse outcomes (p < 0.05). Regression analysis proved myocardial blush grade and diabetes status as independent predictors of percentage increase in ejection fraction (p < 0.05).
High myocardial blush grade is one of the independent predictors of better outcomes in ST-elevation myocardial infarction.
尽管血流已经恢复,但仍可能出现细微的微血管阻塞。这种阻塞可以用心肌灌注分级来评估。我们旨在研究经皮介入治疗后心肌灌注分级对射血分数和不良结局的作用。
本研究在我们的机构进行了一项前瞻性、观察性研究,并计算了样本量。在干预前记录了年龄、性别和射血分数等变量。对患者进行了 3 个月的随访以确定结局。使用 IBM SPSS 软件版本 26.0 对数据进行分析。统计检验的 P 值小于 0.05 被认为具有统计学意义。
研究中有 74 名男性和 36 名女性参与者。平均年龄为 52.20±10.02 岁。最常见的不良结局是心力衰竭(18%)。心肌灌注分级与射血分数改善之间存在显著的 Pearson 相关性(p<0.05)。心肌灌注分级的改善与不良结局的减少显著相关(p<0.05)。回归分析证明心肌灌注分级和糖尿病状态是射血分数增加百分比的独立预测因子(p<0.05)。
高心肌灌注分级是 ST 段抬高型心肌梗死更好结局的独立预测因子之一。