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[造血干细胞移植的眼部并发症:法语国家骨髓移植与细胞治疗协会(SFGM-TC)指南]

[Hematopoietic stem cell transplantation ocular complications: Guidelines from the Francophone Society of Bone Marrow Transplantation and Cellular Therapy (SFGM-TC)].

作者信息

Borel Cécile, Ahmad Imran, Ceballos Patrice, Desbrosses Yohann, Hamzy Fati, Ravinet Aurélie, Souchet Laetitia, Turlure Pascal, Villate Alban, Yakoub-Agha Ibrahim, Guillaume Thierry

机构信息

Institut universitaire du cancer de Toulouse, service d'hématologie, 1, avenue Irène Joliot-Curie, 31100 Toulouse, France.

Hôpital maisonneuve - Rosemont, service d'hématologie et oncologie médicale, 5415, boulevard de l'Assomption, H1T2M4 Montréal, QC, Canada.

出版信息

Bull Cancer. 2020 Dec;107(12S):S116-S121. doi: 10.1016/j.bulcan.2020.04.014. Epub 2020 Jul 4.

Abstract

INTRODUCTION

Allogeneic stem cell transplantation is currently the only curative therapy for hematological disorders. This treatment can lead to complications, of which ophtalmological involvement.

METHODS

We reviewed the literature and established accessible and convenient recommendations for hematologists and ophthalmologists.

RESULTS

Ophtalmological follow-up should be done in every patient having had an allogeneic transplantation, by the hematologist questioning and by the ophthalmologist physical exam. Complications due to graft-versus-host disease (GVHD) or not due to GVHD are cited, as well as therapeutic options.

DISCUSSION

Screening and treatment of ophthalmologic complications in allogeneic stem cells transplantation recipients requires a close collaboration between hematologists and ophthalmologists. The management of these patients by caregivers trained in these questions is encouraged.

摘要

引言

同种异体干细胞移植是目前治疗血液系统疾病的唯一治愈性疗法。这种治疗可能会导致并发症,其中包括眼部受累。

方法

我们回顾了文献,并为血液科医生和眼科医生制定了易于获取且方便的建议。

结果

每位接受过同种异体移植的患者都应进行眼科随访,由血液科医生询问情况并由眼科医生进行体格检查。文中列举了移植物抗宿主病(GVHD)或非GVHD导致的并发症以及治疗选择。

讨论

同种异体干细胞移植受者眼部并发症的筛查和治疗需要血液科医生和眼科医生密切合作。鼓励由接受过这些问题培训的护理人员对这些患者进行管理。

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