Departamento de Zootecnia, Universidade Federal da Bahia, Salvador, BA, Brazil.
Embrapa Tabuleiros Costeiros, Brasilia, SE, Brazil.
Anim Biotechnol. 2022 Apr;33(2):201-213. doi: 10.1080/10495398.2020.1781651. Epub 2020 Jul 7.
Myostatin and MyoD family genes play vital roles in myogenesis and this study aimed to identify association of variants in , , , , and genes with meat traits in Santa Inês sheep. A dataset with 44 variants and records of seven meat traits in 192 lambs (pH0, pH24, a*, b*, L*, tenderness assessed by shear force, and water-holding capacity) was used. Single-locus and haplotype association analyses were performed, and the significance threshold was established according to Bonferroni's method. Single-locus analysis revealed two associations at a Bonferroni level, where the variant in had an additive effect (-4.31 ± 1.08 N) on tenderness, while the variant in had an additive effect (-2.86 ± 0.64) on a*. Additionally, the haplotype replacement > in was associated with pH0 (1.26 ± 0.31), pH24 (1.07 ± 0.27), a* (-1.40 ± 0.51), and tenderness (3.83 ± 1.22 N), while the replacement in was associated with pH0 (1.43 ± 0.26), pH24 (1.25 ± 0.22), b* (-1.06 ± 0.39), and tenderness (-4.13 ± 1.16 N). Our results have demonstrated that some variants in , , , and can be associated with physicochemical meat traits in Santa Inês sheep.
肌肉生长抑制素和 MyoD 家族基因在肌肉发生中起着至关重要的作用，本研究旨在鉴定 、 、 、 和 基因中的变异与 Santa Inês 绵羊肉质性状的关联。使用了一个包含 44 个变异和 192 只羔羊 7 个肉质性状记录（pH0、pH24、a*、b*、L*、剪切力评估的嫩度和水分保持能力）的数据集。进行了单基因座和单倍型关联分析，并根据 Bonferroni 方法确定了显著性阈值。单基因座分析显示，在 Bonferroni 水平上有两个关联， 中的变异 对嫩度有累加效应（-4.31±1.08 N）， 中的变异 对 a有累加效应（-2.86±0.64）。此外， 中的单倍型替换 >与 pH0（1.26±0.31）、pH24（1.07±0.27）、a（-1.40±0.51）和嫩度（3.83±1.22 N）相关，而 中的替换 与 pH0（1.43±0.26）、pH24（1.25±0.22）、b*（-1.06±0.39）和嫩度（-4.13±1.16 N）相关。我们的结果表明， 、 、 、 和 中的一些变异可以与 Santa Inês 绵羊的肉品质性状相关。
