UF Health Shands Transplant Center, Division of Transplantation and Hepatobiliary Surgery, University of Florida, Gainesville, Florida, United States.
Curr Pharm Des. 2020;26(28):3418-3424. doi: 10.2174/1381612826666200707131857.
Visceral transplant represents an immunologic challenge due to high intestinal graft immunogenicity. Over the last 20 years, significant advances in immunosuppression regimens have resulted in excellent short-term outcomes. Currently, visceral transplant is the standard of care for patients with gut failure having life-threatening complications and complex abdominal pathology. In this review, we describe immunosuppressive strategies in the visceral transplant field.
内脏移植由于肠移植物的高免疫原性而构成免疫挑战。在过去的 20 年中，免疫抑制方案的重大进展带来了出色的短期结果。目前，对于有生命威胁的并发症和复杂腹部病理的肠道衰竭患者，内脏移植是标准的治疗方法。在这篇综述中，我们描述了内脏移植领域的免疫抑制策略。
