IEEE Trans Neural Syst Rehabil Eng. 2020 Jul;28(7):1651-1660. doi: 10.1109/TNSRE.2020.2994900.
Ease of use and non-invasiveness has made transcutaneous stimulation a pervasive approach for restoration of hand function. Besides, limited targetability and induced discomfort pose a significant impediment for its clinical translation. By modifying the electrode geometry, we aim to improve the stimulation performance of small surface area electrodes that are suited for forearm muscles. Accordingly, the stimulation performance of twelve electrode geometries was assessed using a computational model and subsequent experimentation on healthy participants. Several metrics quantified their stimulation performance in terms of selectivity, comfort, and safety. Systematic analysis showed that electrode geometries and their underlying currents distribution influence selectivity and comfort, allowing for better stimulation performance. Ranking the electrode geometries identified the concentric serpentine, and the fractal-based Sierpiński and Hibert-types to outperform the circular electrodes. At a comfortable level, these electrodes provoked selective and substantial muscle contraction. Ideally, these geometries can be a reference for optimal electrode designs. The novelty of this study lies with both model-based and experimental assessments on a wide range of electrode geometries and the introduction of a computational model for electrode performance evaluation. Implications from this study can aid with easy to fabricate and personalized electrode designs. By integrating these optimized electrode designs with advanced material technologies, the applicability of wearable neuroprostheses can be improved.
经皮刺激由于其使用方便且无创,已成为手部功能恢复的一种普遍方法。然而,其靶向性有限和引起的不适仍然是其临床转化的重大障碍。通过修改电极几何形状,我们旨在改善适用于前臂肌肉的小面积电极的刺激性能。为此,我们使用计算模型评估了十二种电极几何形状的刺激性能,并在健康参与者身上进行了后续实验。我们使用了一些指标来量化它们在选择性、舒适性和安全性方面的刺激性能。系统分析表明,电极几何形状及其下的电流分布会影响选择性和舒适性,从而实现更好的刺激性能。对电极几何形状进行排名后发现,同心蛇形、分形的 Sierpiński 和 Hibert 型比圆形电极表现更好。在舒适水平下,这些电极可引发选择性和显著的肌肉收缩。理想情况下,这些几何形状可以作为最佳电极设计的参考。本研究的新颖之处在于对广泛的电极几何形状进行了基于模型和实验评估,并引入了一种用于评估电极性能的计算模型。这项研究的意义在于可以帮助设计出易于制造和个性化的电极。通过将这些优化的电极设计与先进的材料技术相结合,可以提高可穿戴神经假体的适用性。