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克服活体供肝移植中门静脉闭锁性改变的技术。

Techniques for overcoming atretic changes of the portal vein in living donor liver transplantation.

机构信息

Department of Surgery, Seoul National University College of Medicine, 101 Daehak-ro, Jongno-gu, Seoul 03080, Korea.

Department of Surgery, Seoul National University College of Medicine, 101 Daehak-ro, Jongno-gu, Seoul 03080, Korea.

出版信息

Hepatobiliary Pancreat Dis Int. 2020 Aug;19(4):311-317. doi: 10.1016/j.hbpd.2020.06.016. Epub 2020 Jun 30.

Abstract

BACKGROUND

Spontaneous diversion of the portal flow through collateral vessels into the systemic circulation is frequently observed in liver transplant recipients with severe portal hypertension. This induces main portal vein atretic change and modifies flow into the collateral even after donor graft implantation. These atretic changes make liver transplantation challenging. In this article we described several methods for overcoming this challenge by appropriate surgical techniques.

METHODS

Three anastomotic techniques for living donor liver transplantation were performed in patients with atretic changes in the portal vein.

RESULTS

The three techniques were (1) venoplasty to widen the diameter by using the recipient's portal vein, and the diameter of the recipient's portal vein was enlarged using their own portal vein stump patch; (2) conduit with cryopreserved vessels, and we dissected around the superior mesenteric vein and splenic vein junction and a conduit was built using the cryopreserved vessels; and (3) left gastric varix to portal vein anastomosis, if the recipients had large gastric varix and variceal wall was sufficiently thick for anastomosis.

CONCLUSIONS

Selection of optimal methods for portal vein anastomosis is essential in patients with atrophic change on the portal vein. If these methods are used aptly, they can be considered as favorable methods for overcoming each situation.

摘要

背景

严重门静脉高压的肝移植受者中,经常观察到门静脉血流通过侧支血管自发分流到体循环。这会导致主门静脉闭塞性改变,并在供体移植物植入后改变侧支的血流。这些闭塞性改变使肝移植变得具有挑战性。在本文中,我们描述了通过适当的手术技术克服这一挑战的几种方法。

方法

对门静脉闭塞性改变的患者采用三种活体供肝肝移植吻合技术。

结果

三种技术分别为:(1)使用受者门静脉进行血管成形术以扩大其直径,并使用受者自身门静脉残端修补片扩大受者门静脉的直径;(2)使用冷冻保存血管的导管,我们在肠系膜上静脉和脾静脉交界处进行解剖,并使用冷冻保存血管构建导管;(3)如果受者有大的胃静脉曲张且静脉曲张壁足够厚适合吻合,可以进行胃左静脉至门静脉吻合术。

结论

在门静脉有萎缩性改变的患者中,选择最佳的门静脉吻合方法至关重要。如果这些方法应用得当,可以认为它们是克服每种情况的有利方法。

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