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多学科老年康复计划的血液动力学效应。

Hemodynamic Effects of a Multidisciplinary Geriatric Rehabilitation Program.

机构信息

University Hospital Marien Hospital Herne, Department of Internal Medicine I, Ruhr-University Bochum, Bochum, Germany.

University Hospital Brandenburg, Department of Cardiology, Brandenburg Medical School, Brandenburg an der Havel, Germany.

出版信息

Clin Interv Aging. 2020 Jun 30;15:1035-1043. doi: 10.2147/CIA.S239844. eCollection 2020.

Abstract

BACKGROUND

Geriatric rehabilitation programs primarily aim at an increase of mobility and functional autonomy of the elderly. The cardiovascular effects of these programs, however, remain elusive. Since regular physical exercise is associated with numerous beneficial cardiovascular effects including a reduction of blood pressure (BP), the present prospective study investigates the hemodynamic effects of a representative standardized rehabilitation program.

METHODS

A total of 74 subjects who were hospitalized in a German university hospital for geriatric rehabilitation were enrolled in the study. Peripheral BP, central aortic BP, 24h-ambulatory BP, heart rate and pulse wave velocity as a measure of arterial stiffness were assessed at admission and before discharge from the hospital. The program contained 4-5 sessions of physical activity of individualized intensity per week (≥30 min/session, eg, walking, cycling, stair rising).

RESULTS

The mean age of the study population was 82.4±6.9 years; all patients suffered from arterial hypertension (stage 2-3) with a median number of three antihypertensive drugs. The most frequent cause for admission was injurious falls. The mean duration of the rehabilitation program was 17 days and comprised at least 20 physical activity sessions including occupational therapy. The program led to a significant improvement of mobility (Timed Up & Go 29.5±18.5 vs 19.1 ±9.3 s, p<0.001) and Barthel index of activities of daily living score (46.6±19.1 vs 69.8±16.5, p<0.001). Peripheral systolic BP decreased from 135.4±19.0 mmHg at baseline to 129.0±18.4 mmHg at follow-up (p=0.03), whereas peripheral diastolic BP, central aortic BP, 24h-ambulatory BP, heart rate and pulse wave velocity as a measure of arterial stiffness were not significantly altered (p>0.05 each).

CONCLUSION

The present representative standardized geriatric rehabilitation program was able to improve mobility, which showed a mild effect on systolic BP but did not affect 24h-ambulatory BP.

摘要

背景

老年康复计划主要旨在提高老年人的活动能力和功能独立性。然而,这些计划对心血管的影响仍不清楚。由于定期体育锻炼与许多有益的心血管作用有关,包括降低血压(BP),本前瞻性研究调查了代表标准化康复计划的血流动力学影响。

方法

共有 74 名在德国大学医院接受老年康复治疗的患者参加了这项研究。在入院时和出院前评估了外周血压、中心主动脉血压、24 小时动态血压、心率和脉搏波速度作为动脉僵硬的指标。该计划每周包含 4-5 次个体化强度的身体活动(≥30 分钟/次,例如,散步、骑自行车、爬楼梯)。

结果

研究人群的平均年龄为 82.4±6.9 岁;所有患者均患有动脉高血压(2-3 期),中位数服用三种降压药。入院的最常见原因是受伤性跌倒。康复计划的平均持续时间为 17 天,包括至少 20 次体育活动,包括职业治疗。该计划显著改善了活动能力(计时起立行走测试 29.5±18.5 秒比 19.1 ±9.3 秒,p<0.001)和日常生活活动评分的巴氏指数(46.6±19.1 比 69.8±16.5,p<0.001)。外周收缩压从基线时的 135.4±19.0mmHg 降至随访时的 129.0±18.4mmHg(p=0.03),而外周舒张压、中心主动脉血压、24 小时动态血压、心率和脉搏波速度作为动脉僵硬的指标无明显变化(p>0.05)。

结论

本研究代表了标准化的老年康复计划能够提高活动能力,对收缩压有轻微影响,但对 24 小时动态血压没有影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f78c/7335293/4ccc432918a0/CIA-15-1035-g0001.jpg

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