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一名B淋巴细胞白血病患者坏死性软组织感染的诊断挑战

Diagnostic Challenge of Necrotizing Soft Tissue Infection in a Patient With B Lymphocytic Leukemia.

作者信息

Sadauskas Andrius, Jukneviciene Renata, Pečeliūnas Valdas, Masionis Povilas, Kvederas Giedrius

机构信息

Trauma, Institute of Clinical Medicine, Clinic of Rheumatology, Orthopaedic Traumatology and Reconstructive Surgery, Centre of Orthopedics and Traumatology, Vilnius University Hospital Santaros Clinics, Vilnius University Faculty of Medicine, Vilnius, LTU.

Emergency Medicine, Institute of Clinical Medicine, Clinic of Emergency Medicine, Centre of Emergency Medicine, Vilnius University Hospital Santaros Clinics, Vilnius University Faculty of Medicine, Vilnius, LTU.

出版信息

Cureus. 2020 Jun 1;12(6):e8387. doi: 10.7759/cureus.8387.

Abstract

The necrotizing soft tissue infection is a rare surgical emergency. Early diagnosis and timely treatment can contribute to better survival and the preservation of the limb. Diagnosis of this pathology remains a challenge to the clinician at the initial stage of the disease, especially if the patient is immunocompromised. We present the case of a 75-year-old man with B lymphocytic leukemia who was diagnosed with necrotizing soft tissue infection but failed to exhibit typical clinical and laboratory measurements. This case highlights the difficulty of early diagnosis in hematology patient, altered sensitivity of disease-specific scoring systems, and importance of high clinician awareness.

摘要

坏死性软组织感染是一种罕见的外科急症。早期诊断和及时治疗有助于提高生存率并保住肢体。在疾病的初始阶段,对这种病症的诊断对临床医生来说仍然是一项挑战,尤其是当患者免疫功能低下时。我们报告一例75岁患B淋巴细胞白血病的男性病例,该患者被诊断为坏死性软组织感染,但未表现出典型的临床和实验室指标。该病例凸显了血液学患者早期诊断的困难、疾病特异性评分系统敏感性的改变以及临床医生高度警觉的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/203a/7331898/a7aa9f6ca1da/cureus-0012-00000008387-i01.jpg

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