Huynh Philip, Victor Grant, Ray Brad
Center for Behavioral Health and Justice at Wayne State University, Detroit, MI, United States.
Addict Behav Rep. 2020 Jun 8;12:100289. doi: 10.1016/j.abrep.2020.100289. eCollection 2020 Dec.
Overdose deaths have increased dramatically in the United States and are often attributed to prescription opioids. This study presents a framework for "overdose typologies", including non-medical prescription drug use, to more accurately describe drug use patterns.
This study examined linked prescription drug monitoring program (PDMP) and toxicology data (2016-2018) from accidental overdose deaths from a large metropolitan coroner's office in the Midwest (Indianapolis, Indiana).
In total, 1,112 accidental overdose deaths occurred and over two-thirds (68.0%; n = 756) were coded as an illicit drug user with no prescription opioid present in the toxicology. The most infrequent categories were prescription opioid users 5.5% (n = 61).
Linked PDMP and toxicology reports are useful in identifying drug use patterns that contribute to mortality.
美国的过量用药死亡人数急剧增加，且往往归因于处方阿片类药物。本研究提出了一个“过量用药类型学”框架，包括非医疗目的的处方药使用，以更准确地描述药物使用模式。
本研究检查了来自中西部一个大型都市验尸官办公室（印第安纳波利斯，印第安纳州）的意外过量用药死亡案例中，处方药物监测计划（PDMP）与毒理学数据的关联情况（2016 - 2018年）。
总共发生了1112例意外过量用药死亡案例，超过三分之二（68.0%；n = 756）被编码为非法药物使用者，毒理学检测中未发现处方阿片类药物。最不常见的类别是处方阿片类药物使用者，占5.5%（n = 61）。
关联的PDMP和毒理学报告有助于识别导致死亡的药物使用模式。
