Waring J P, Sanowski R A
Division of Gastroenterology, Carl T. Hayden Veterans Administration Medical Center, Phoenix, Arizona.
Am J Gastroenterol. 1988 Nov;83(11):1245-7.
Esophageal stricture is a common complication of endoscopic variceal sclerotherapy (EVS). The belief was that it could be managed safely and easily by esophageal dilation. Of 103 patients treated at our institution with EVS, 31 developed strictures, and of these, five have presented with food impaction (16.1%), a previously unreported complication. Three of the five had undergone prior esophageal dilation. Our patients received an average of 89 ml of 1.5% sodium tetradecyl in 7.6 sessions, compared with 51 ml in three sessions in an earlier group of EVS-induced strictures without food impaction. Esophageal manometric abnormalities were seen in three of four patients studied, two with markedly impaired peristaltic activity. All patients had successful treatment of both esophageal stricture and bleeding varices. Further sclerotherapy continued in four of five patients without additional problems. Food impaction in EVS-induced esophageal stricture can occur, despite dilation therapy.
食管狭窄是内镜下静脉曲张硬化治疗(EVS)的常见并发症。过去认为通过食管扩张可以安全简便地处理该并发症。在我院接受EVS治疗的103例患者中,31例发生了狭窄,其中5例出现食物嵌塞(16.1%),这是一种此前未报道过的并发症。5例中有3例曾接受过食管扩张。我们的患者平均在7.6次治疗中接受了89毫升的1.5%十四烷基硫酸钠,而早期一组未发生食物嵌塞的EVS所致狭窄患者在3次治疗中平均接受51毫升。在接受研究的4例患者中,3例出现食管测压异常,其中2例蠕动功能明显受损。所有患者的食管狭窄和曲张静脉出血均成功治愈。5例患者中有4例继续进行硬化治疗,未出现其他问题。尽管进行了扩张治疗,EVS所致食管狭窄仍可能发生食物嵌塞。