Department of Pathology, Hamidiye Medical Faculty, Haydarpaşa Numune Training and Research Hospital, University of Health Sciences Turkey, İstanbul, Turkey.
Department of Dermatology, Hamidiye Medical Faculty, Haydarpaşa Numune Training and Research Hospital, University of Health Sciences Turkey, İstanbul, Turkey.
J Cutan Pathol. 2020 Dec;47(12):1159-1163. doi: 10.1111/cup.13800. Epub 2020 Sep 10.
A case of adult-onset longitudinal melanonychia caused by a compound nevus is described. Longitudinal melanonychias are mainly caused by melanocytic activation (hypermelanosis), lentigo (benign melanocytic hyperplasia), nevus, and melanoma. Nevi are more commonly seen in children than adults; however, melanocytic activation, atypical melanocytic proliferation, and melanoma are more frequent in adults. The majority of nail matrix nevi causing longitudinal melanonychia first appear in childhood and are junctional. Rarely, compound nevi are reported to cause longitudinal melanonychia in childhood.
本文描述了一例由复合痣引起的成人发病的纵向黑甲。纵向黑甲主要由黑素细胞激活(色素沉着过度)、雀斑(良性黑素细胞增生)、痣和黑色素瘤引起。痣在儿童中比在成人中更常见;然而,在成人中,黑素细胞激活、非典型性黑素细胞增生和黑色素瘤更为常见。引起纵向黑甲的大多数甲母痣首先在儿童时期出现,且为交界痣。罕见情况下,有文献报道复合痣也可引起儿童纵向黑甲。