Gilardi M C, Bettinardi V, Todd-Pokropek A, Milanesi L, Fazio F
ITBA, CNR Milano, Italy.
J Nucl Med. 1988 Dec;29(12):1971-9.
The detection of scattered radiation is recognized as one of the major sources of error in single photon emission computed tomography (SPECT). In this work three scatter correction techniques have been assessed and compared. Scatter coefficients and parameters characteristic of each technique have been calculated through Monte Carlo simulations and experimentally measured for various source geometries. Their dependence on the source/matter distribution and their spatial non-stationarity have been described. Each of the three scatter correction methods has then been tested on several SPECT phantom studies. The three methods provided comparable results. Following scatter compensation, both image quality and quantitative accuracy improved. In particular a slight improvement in spatial resolution and a statistically significant increase in cold lesion contrast, hot lesion recovery coefficient, and signal/noise ratio have been demonstrated with all methods.
散射辐射的检测被认为是单光子发射计算机断层扫描（SPECT）中主要的误差来源之一。在这项工作中，对三种散射校正技术进行了评估和比较。通过蒙特卡罗模拟计算了每种技术的散射系数和特征参数，并针对各种源几何形状进行了实验测量。描述了它们对源/物质分布的依赖性及其空间非平稳性。然后，在几个SPECT体模研究中对这三种散射校正方法分别进行了测试。这三种方法提供了可比的结果。进行散射补偿后，图像质量和定量准确性均有所提高。特别是，所有方法均显示出空间分辨率略有提高，冷病灶对比度、热病灶恢复系数和信噪比在统计学上有显著增加。
