使用透射数据对投影集进行衰减校正的定量单光子发射计算机断层显像：一种方法的评估
Quantitative SPECT by attenuation correction of the projection set using transmission data: evaluation of a method.
作者信息
Almquist H, Palmer J, Ljungberg M, Wollmer P, Strand S E, Jonson B
机构信息
Department of Clinical Physiology, University of Lund, Sweden.
出版信息
Eur J Nucl Med. 1990;16(8-10):587-94. doi: 10.1007/BF00998154.
A method for measuring attenuation coefficients in single-photon emission tomography (SPECT) is described and evaluated, together with a method for attenuation correction using these measured attenuation coefficients. Build-up, caused by scattered photons, is corrected for by a simple substitution in the algorithms. Transmission studies are performed with a 99mTc- or 57Co flood source, and emission phantom studies with 99mTc line sources. The method is evaluated with variable but well-defined phantoms. The result is accurate attenuation coefficients for different densities, dimensions and geometries, and an accuracy of corrected emission activities of better than +/- 10% in most cases. The present limitations of the method for attenuation correction are discussed.
本文描述并评估了一种在单光子发射断层扫描（SPECT）中测量衰减系数的方法，以及一种使用这些测量得到的衰减系数进行衰减校正的方法。算法中通过简单替换对由散射光子引起的积累效应进行了校正。使用99mTc或57Co泛源进行透射研究，使用99mTc线源进行发射体模研究。该方法通过可变但定义明确的体模进行评估。结果得到了不同密度、尺寸和几何形状下准确的衰减系数，并且在大多数情况下，校正后发射活度的准确度优于±10%。文中还讨论了该衰减校正方法目前存在的局限性。
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