Internal Medicine Research Unit, Pfizer Worldwide Research, Discovery and Medical, Cambridge, MA, USA.
Internal Medicine Research Unit, Pfizer Worldwide Research, Discovery and Medical, Cambridge, MA, USA.
Cell Metab. 2020 Jul 7;32(1):6-8. doi: 10.1016/j.cmet.2020.06.009.
The abundance of dietary sweeteners and overconsumption of fructose are widely thought to promote metabolic disease. In this issue of Cell Metabolism, Andres-Hernando et al. (2020) identify the liver as the major site of fructose metabolism-mediated metabolic dysfunction and identify a surprising role for intestinal fructose metabolism in driving fructose intake.
人们普遍认为，饮食中甜味剂的丰富和果糖的过度摄入会促进代谢疾病。在本期《细胞代谢》杂志中，Andres-Hernando 等人（2020 年）确定肝脏是果糖代谢介导的代谢功能障碍的主要部位，并发现肠道果糖代谢在驱动果糖摄入方面起着令人惊讶的作用。
