体质消瘦：说空话还是做实事？
Constitutional Thinness: tALKing the tALK or wALKing the wALK?
机构信息
MRC Metabolic Diseases Unit, Wellcome Trust-Medical Research Council Institute of Metabolic Science, Cambridge, UK.
MRC Metabolic Diseases Unit, Wellcome Trust-Medical Research Council Institute of Metabolic Science, Cambridge, UK; Department of Clinical Biochemistry, University of Cambridge, Cambridge, UK; Cambridge NIHR Biomedical Research Centre, Cambridge, UK; Addenbrooke's Hospital, Cambridge, UK.
出版信息
Cell Metab. 2020 Jul 7;32(1):8-10. doi: 10.1016/j.cmet.2020.06.012.
In a recent issue of Cell, Orthofer et al. (2020) present a body of data from mice, flies, and humans that suggest (1) a physiological role for Alk in the normal control of energy balance across several species and (2) a possible contribution of genetic variants in or near ALK to the variability of adiposity in humans, more specifically at its lower end.
在最近一期的《细胞》杂志上，Orthofer 等人（2020 年）展示了来自小鼠、果蝇和人类的数据，这些数据表明：（1）Alk 在几种物种的能量平衡的正常控制中具有生理作用；（2）ALK 内或附近的遗传变异可能对人类肥胖的可变性，特别是肥胖的下限，有一定的影响。
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