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本文引用的文献

1
Is tofacitinib a game-changing drug for ulcerative colitis?托法替布是否为溃疡性结肠炎带来变革性药物？
United European Gastroenterol J. 2020 Aug;8(7):755-763. doi: 10.1177/2050640620935732. Epub 2020 Jun 18.
2
Tofacitinib for ulcerative colitis: results of the prospective Dutch Initiative on Crohn and Colitis (ICC) registry.托法替尼治疗溃疡性结肠炎：前瞻性荷兰克罗恩病和结肠炎倡议（ICC）注册研究结果。
Aliment Pharmacol Ther. 2020 May;51(9):880-888. doi: 10.1111/apt.15689. Epub 2020 Apr 1.
3
JAK-STAT pathway targeting for the treatment of inflammatory bowel disease.JAK-STAT 通路靶向治疗炎症性肠病。
Nat Rev Gastroenterol Hepatol. 2020 Jun;17(6):323-337. doi: 10.1038/s41575-020-0273-0. Epub 2020 Mar 19.
4
First- and Second-Line Pharmacotherapies for Patients With Moderate to Severely Active Ulcerative Colitis: An Updated Network Meta-Analysis.中重度活动型溃疡性结肠炎患者的一线和二线药物治疗：一项更新的网络荟萃分析。
Clin Gastroenterol Hepatol. 2020 Sep;18(10):2179-2191.e6. doi: 10.1016/j.cgh.2020.01.008. Epub 2020 Jan 13.
5
New biologics and small molecules in inflammatory bowel disease: an update.炎症性肠病中的新型生物制剂和小分子药物：最新进展
Therap Adv Gastroenterol. 2019 May 26;12:1756284819853208. doi: 10.1177/1756284819853208. eCollection 2019.
6
Efficacy of Induction Therapy With High-Intensity Tofacitinib in 4 Patients With Acute Severe Ulcerative Colitis.4 例急性重度溃疡性结肠炎患者应用高强度托法替布诱导治疗的疗效。
Clin Gastroenterol Hepatol. 2019 Apr;17(5):988-990.e1. doi: 10.1016/j.cgh.2018.11.022. Epub 2018 Nov 17.
7
ESCMID Study Group for Infections in Compromised Hosts (ESGICH) Consensus Document on the safety of targeted and biological therapies: an infectious diseases perspective (Intracellular signaling pathways: tyrosine kinase and mTOR inhibitors).欧洲临床微生物学和传染病学会（ESCMID）感染宿主研究组（ESGICH）关于靶向和生物治疗安全性的共识文件：传染病学视角（细胞内信号通路：酪氨酸激酶和 mTOR 抑制剂）。
Clin Microbiol Infect. 2018 Jun;24 Suppl 2:S53-S70. doi: 10.1016/j.cmi.2018.02.009. Epub 2018 Feb 16.
8
Tofacitinib as Induction and Maintenance Therapy for Ulcerative Colitis.托法替布治疗溃疡性结肠炎的诱导缓解和维持治疗。
N Engl J Med. 2017 May 4;376(18):1723-1736. doi: 10.1056/NEJMoa1606910.
9
Tofacitinib for induction and maintenance therapy of Crohn's disease: results of two phase IIb randomised placebo-controlled trials.托法替布用于克罗恩病的诱导和维持治疗：两项IIb期随机安慰剂对照试验的结果
Gut. 2017 Jun;66(6):1049-1059. doi: 10.1136/gutjnl-2016-312735. Epub 2017 Feb 16.

Tofacitinib, two-faced Janus in ulcerative colitis and Crohn's disease?

作者信息

Biemans Vince Bc, Verstockt Bram

机构信息

Department of Gastroenterology and Hepatology, Radboud University Medical Centre, Nijmegen, The Netherlands.

Department of Gastroenterology and Hepatology, Maastricht University Medical Center, Maastrict, The Netherlands.

出版信息

United European Gastroenterol J. 2020 Aug;8(7):753-754. doi: 10.1177/2050640620942641. Epub 2020 Jul 8.

DOI:10.1177/2050640620942641
PMID:32640933
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7434994/
Abstract
摘要