Faculty of Medicine and University Hospital Cologne, Department I for Internal Medicine, University of Cologne, Herderstr. 52-54, 50931, Cologne, Germany.
German Center for Infection Research (DZIF), partner site Bonn-Cologne, Cologne, Germany.
BMC Bioinformatics. 2020 Jul 8;21(1):290. doi: 10.1186/s12859-020-03596-1.
Well-characterized biomaterials of high quality have great potential for acceleration and quality improvement in translational biomedical research. To improve accessibility of local sample collections, efforts have been made to create central biomaterial banks and catalogues. Available technical solutions for creating professional local sample catalogues and connecting them to central systems are cost intensive and/or technically complex to implement. Therefore, the Translational Thematic Unit HIV of the German Center for Infection Research (DZIF) developed a Laboratory Information and Management System (LIMS) called HIV Engaged Research Technology (HEnRY) for implementation into the Translational Platform HIV (TP-HIV) at the DZIF and other research networks.
HEnRY is developed at the University Hospital of Cologne. It is an advanced LIMS to manage processing and storage of samples and aliquots of different sample types. Features include: monitoring of stored samples and associated information data selection via query tools or Structured Query Language (SQL) preparation of summary documents, including scannable search lists centralized management of the practical laboratory part of multicentre studies (e.g. import of drawing schemes and sample processing steps), preparation of aliquot shipments, including associated documents to be added to shipments unique and secure identification of aliquots through use of customizable Quick Response (QR) code labels directly from HEnRY support of aliquot data transmission to central registries. In summary, HEnRY offers all features necessary for a LIMS software. In addition, the structure of HEnRY provides sufficient flexibility to allow the implementation in other research areas.
HEnRY is a free biobanking tool published under the MIT license. While it was developed to support HIV research in Germany, the feature set and language options, allow much broader applications and make this a powerful free research tool.
高质量的特征明确的生物材料在加速转化医学研究和提高研究质量方面具有巨大潜力。为了提高本地样本采集的便利性，已经努力创建了中央生物材料库和目录。创建专业的本地样本目录并将其连接到中央系统的现有技术解决方案实施成本高且/或技术上复杂。因此，德国感染研究中心（DZIF）的转化专题单位 HIV 开发了一种称为 HIV 参与研究技术（HEnRY）的实验室信息和管理系统（LIMS），用于在 DZIF 和其他研究网络中的转化平台 HIV（TP-HIV）中实施。
HEnRY 由科隆大学医院开发。它是一种先进的 LIMS，用于管理不同样本类型的处理和存储以及样本等分。其特点包括：通过查询工具或结构化查询语言（SQL）监控存储样本和相关信息数据选择、准备包括可扫描搜索列表的摘要文档、集中管理多中心研究的实际实验室部分（例如，导入绘图方案和样本处理步骤）、准备等分发货，包括要添加到发货的相关文件、通过使用可定制的快速响应（QR）码标签从 HEnRY 直接对等分进行唯一和安全识别、支持将等分数据传输到中央登记处。总之，HEnRY 提供了 LIMS 软件所需的所有功能。此外，HEnRY 的结构提供了足够的灵活性，允许在其他研究领域实施。
HEnRY 是一个根据 MIT 许可证发布的免费生物银行工具。虽然它是为支持德国的 HIV 研究而开发的，但它的功能集和语言选项允许更广泛的应用，并使其成为一个强大的免费研究工具。
