Marceddu Giuseppe, Dallavilla Tiziano, Xhuvani Aleksander, Daja Muharrem, De Antoni Luca, Casadei Arianna, Bertelli Matteo
MAGI Euregio, Bolzano, Italy.
MAGI'S Lab, Rovereto (TN), Italy.
Acta Biomed. 2020 Nov 9;91(13-S):e2020015. doi: 10.23750/abm.v91i13-S.10521.
The increasing demand for genetic testing for clinical diagnosis and research challenges genetic laboratory capacity to track an increasing number of patient samples through all steps of analysis, from sample collection to report generation. This task is usually performed with the help of a laboratory information management system (LIMS), software that makes it possible to collect, store and retrieve laboratory and sample data. To date there are no open-source options that can manage the entire analytical flow of a genetic laboratory. appMAGI seeks to include all the management aspects of a clinical diagnostic laboratory, making it simpler to process many samples while maintaining the high security and quality standards required in clinical diagnostic practice.
appMAGI is written in python using Django. It is a web application that does not require local installation, making development, updates and maintenance a much easier task. appMAGI runs on the Ubuntu server and uses SQLite as engine database.
In this work we describe an innovative LIMS called appMAGI designed to support all aspects of a clinical diagnostic laboratory. appMAGI can track samples throughout the diagnostic workflow and NGS analysis by virtue of a customizable bioinformatics pipeline. It can handle sample non-compliance, manage laboratory stocks, help generate reports and provide insights into sample data by means of special tools.
appMAGI is a LIMS endowed with all the features required to manage thousands of samples. Allowing efficient management of patient samples from sample collection to diagnostic report generation.
临床诊断和研究对基因检测的需求不断增加,这对基因实验室在从样本采集到报告生成的所有分析步骤中追踪越来越多患者样本的能力提出了挑战。这项任务通常借助实验室信息管理系统(LIMS)来完成,该软件能够收集、存储和检索实验室及样本数据。到目前为止,尚无能够管理基因实验室整个分析流程的开源选项。appMAGI旨在涵盖临床诊断实验室的所有管理方面,使处理大量样本更加简便,同时维持临床诊断实践所需的高安全性和质量标准。
appMAGI使用Django以Python编写。它是一个无需本地安装的Web应用程序,使开发、更新和维护变得更加轻松。appMAGI运行在Ubuntu服务器上,并使用SQLite作为引擎数据库。
在这项工作中,我们描述了一种名为appMAGI的创新型LIMS,旨在支持临床诊断实验室的各个方面。appMAGI凭借可定制的生物信息学流程,能够在整个诊断工作流程和NGS分析过程中追踪样本。它可以处理样本不合规情况,管理实验室库存,帮助生成报告,并通过特殊工具提供对样本数据的洞察。
appMAGI是一种具备管理数千个样本所需全部功能的LIMS。能够高效管理从样本采集到诊断报告生成的患者样本。