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科学证据的综合：对系统评价和荟萃分析方法的批判性评估

The synthesis of scientific shreds of evidence: a critical appraisal on systematic review and meta-analysis methodology.

作者信息

Bertolaccini Luca, Spaggiari Lorenzo

机构信息

Department of Thoracic Surgery, IEO, European Institute of Oncology IRCCS, Milan, Italy.

Department of Oncology and Hemato-Oncology, University of Milan, Milan, Italy.

出版信息

J Thorac Dis. 2020 Jun;12(6):3399-3403. doi: 10.21037/jtd.2020.03.07.

DOI:10.21037/jtd.2020.03.07
PMID:32642265
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7330768/
Abstract

Synthesising results across studies to recognise the causes of variation in outcomes and to reach an overall understanding of a problem is a crucial part of the scientific method. Until in recent times, the results of scientific findings have been summarised in narrative reviews where the summary of transparent and objective results have become increasingly difficult. Systematic reviews and meta-analyses, conducted by subsequent strict protocols to guarantee reproducibility and decrease bias, have become more common in the synthesis of evidence.

摘要

综合各项研究的结果以识别结果差异的原因并全面理解问题，是科学方法的关键部分。直到最近，科学发现的结果一直是在叙述性综述中进行总结，而在这种综述中，对透明和客观结果的总结变得越来越困难。通过后续严格方案进行的系统综述和荟萃分析，以保证可重复性并减少偏差，在证据综合方面变得更加普遍。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/68f0/7330768/73b6f8d4b4ca/jtd-12-06-3399-f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/68f0/7330768/70dd1cda2f2e/jtd-12-06-3399-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/68f0/7330768/5c6646f9a6be/jtd-12-06-3399-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/68f0/7330768/73b6f8d4b4ca/jtd-12-06-3399-f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/68f0/7330768/70dd1cda2f2e/jtd-12-06-3399-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/68f0/7330768/5c6646f9a6be/jtd-12-06-3399-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/68f0/7330768/73b6f8d4b4ca/jtd-12-06-3399-f3.jpg

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