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儿童腺病毒性角结膜炎的治疗模式。

The Treatment Models for Adenoviral Keratoconjunctivitis in the Childhood Population.

机构信息

Department of Ophthalmology, University of Health Sciences Dr. Behcet Uz Child Disease and Pediatric Surgery Training and Research Hospital, Izmir, Turkey.

出版信息

Ocul Immunol Inflamm. 2021 Nov 17;29(7-8):1627-1632. doi: 10.1080/09273948.2020.1766510. Epub 2020 Jul 9.

DOI:10.1080/09273948.2020.1766510
PMID:32643975
Abstract

: To examine the effects of treatments performed on children with adenoviral conjunctivitis.: 50 children with Adenoviral keratoconjunctivitis (AK) were evaluated. Patients were divided into four groups according to the medical treatment agents that were used previously. AK symptoms were clinically scored and analyzed. The diagnosis of all children was confirmed by an in-office lateral flow immunoassay.: Fifty patients with AK were included in the study. 24 (48%) were female and 26 (52%) were male. The mean age was 12.88 ± 2.66 (8-17). In PVP-I groups clinical findings shows faster improvement than other groups ( < .05).: Conjunctival irrigation with 2.5% PVP-I is very effective for the treatment of adenoviral conjunctivitis in childhood. Ganciclovir ophthalmic gel 0.15% increases the effect of 2.5% PVP-I on AK, but this was not statistically significant.

摘要

: 目的:探讨腺病毒结膜炎患儿的治疗效果。

方法

对 50 例腺病毒性角结膜炎(AK)患儿进行评估。根据以往使用的药物治疗剂将患儿分为四组。对 AK 症状进行临床评分和分析。所有患儿均通过现场侧向流动免疫测定确诊。

结果

本研究共纳入 50 例 AK 患儿,其中女 24 例(48%),男 26 例(52%);平均年龄为 12.88±2.66 岁(8-17 岁)。在 PVP-I 组中,临床发现的改善速度明显快于其他组(<0.05)。

结论

2.5%PVP-I 结膜冲洗对儿童腺病毒性结膜炎的治疗非常有效。0.15%更昔洛韦眼用凝胶可提高 2.5%PVP-I 对 AK 的疗效,但无统计学意义。

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