Majmundar Vidit D., Syed Hasnain A., Baxi Kalgi
Saint Vincent Hospital, Worcester, MA
Sheikh Zayed Hospital, Lahore
Livedoid vasculopathy is a rare vasculopathy typically characterized by bilateral lower limb lesions. The condition is believed to be caused by thrombus formation in the capillary vasculature due to increased thrombotic activity, decreased fibrinolytic activity, and endothelial damage. Livedoid vasculopathy is 3 times more common in females than in males, especially in patients aged 15 to 50 years. Management involves identifying the lesion and differentiating it from other lower limb lesions, along with a skin biopsy to confirm the diagnosis. There is no definitive first-line treatment, but general measures such as smoking cessation, wound care, and pharmacological measures like anticoagulants and antiplatelets have shown good results. Several newer and experimental therapies have shown promising results in resistant cases. In the past, livedoid vasculopathy has also been referred to as livedo vasculitis, livedoid vasculitis, and livedo reticularis with summer ulceration.
萎缩性硬化性苔藓样血管病是一种罕见的血管病，典型表现为双侧下肢病变。该病被认为是由于血栓形成活性增加、纤溶活性降低和内皮损伤导致毛细血管脉管系统中血栓形成所致。萎缩性硬化性苔藓样血管病在女性中的发病率是男性的3倍，尤其在15至50岁的患者中更为常见。治疗包括识别病变并将其与其他下肢病变区分开来，同时进行皮肤活检以确诊。目前尚无明确的一线治疗方法，但诸如戒烟、伤口护理等一般措施以及抗凝剂和抗血小板等药物治疗已显示出良好效果。几种更新的实验性疗法在难治性病例中已显示出有前景的结果。过去，萎缩性硬化性苔藓样血管病也被称为网状青斑性血管炎、萎缩性苔藓样血管炎和伴有夏季溃疡的网状青斑。
