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去大脑强直和去皮层强直姿势

Decerebrate and Decorticate Posturing

作者信息

Knight James, Decker Lawrence C.

机构信息

King's College Hospital London

Naval Medical Center San Diego

Abstract

Decorticate and decerebrate posturing are both considered pathological posturing responses to usually noxious stimuli from an external or internal source. Both involve stereotypical movements of the trunk and extremities and are typically indicative of significant brain or spinal injury. The Nobel Laurette Charles Sherrington first described decerebrate posturing in 1898 after transecting the brainstems of live monkeys and cats. Synonymous terms for decorticate posturing include abnormal flexion, decorticate rigidity, flexor posturing, or decorticate response. Synonymous terms for decerebrate posturing include abnormal extension, decerebrate rigidity, extensor posturing, or decerebrate response. There is a criticism within the literature of the use of the terms decorticate and decerebrate posturing in clinical contexts due to their association with discrete anatomical locations that, in reality, may not be so prescriptive.  Brain lesions of several anatomical regions may cause both postures, though they do usually involve some degree of brainstem injury. It is, however, accepted that decorticate typically requires an injury more rostral than decerebrate posturing. In most literature, this level is considered the red nucleus at the intercollicular level of the midbrain.

摘要

去皮质强直和去大脑强直均被视为对通常来自外部或内部的有害刺激的病理性姿势反应。两者都涉及躯干和四肢的刻板运动,通常表明存在严重的脑或脊髓损伤。诺贝尔奖获得者查尔斯·谢灵顿于1898年在切断活猴和猫的脑干后首次描述了去大脑强直。去皮质强直的同义词包括异常屈曲、去皮质强直、屈肌姿势或去皮质反应。去大脑强直的同义词包括异常伸展、去大脑强直、伸肌姿势或去大脑反应。由于去皮质强直和去大脑强直这两个术语与离散的解剖位置相关联,而实际上这些位置可能并非如此具有规定性,因此在临床背景下使用这两个术语受到了文献中的批评。几个解剖区域的脑损伤可能会导致这两种姿势,尽管它们通常确实涉及一定程度的脑干损伤。然而,人们公认去皮质强直通常比去大脑强直需要更靠前的损伤。在大多数文献中,这个水平被认为是中脑丘间水平的红核。

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