Acute paronychia is one of the most common infections of the hand. It is usually caused by a breakdown of the seal between the nail plate and the nail fold with infection resulting from subsequent inoculation of bacterial or fungal pathogens. This is typically precipitated by nail-biting, trauma, manicures, ingrown nails, and hangnail manipulation. Abscess involving pus within the soft tissues adjacent to the nail may occur, indicating the need for surgical drainage. From a microbiology perspective, paronychia of the hand is reported to be a polymicrobial infection with mixed aerobic and anaerobic bacterial flora in around 50% of cases. The most common infective pathogen is (including methicillin-resistant (MRSA)), but other aerobic bacteria may include Sspecies or gram-negative bacteria. While anaerobic florae such as species, or are associated with exposure to oral secretions through nail-biting and digital sucking practices (more common in children). Clinical history and local antibiotic guidance, including consideration of MRSA rates, should direct the prescription of antibiotics. Non-bacterial infections are less common but may include fungal infections such as and viral infections such as herpes simplex. If a paronychia has been present for less than six weeks, it is classified as acute, whereas those present for six weeks or more are classified as chronic. Chronic paronychia is a multifactorial inflammatory condition primarily caused by exposure to environmental allergens or irritants. The disruption to the protective barrier caused by this inflammatory process may result in colonization with bacterial or fungal organisms. Candida is the most commonly implicated micro-organism. With differing etiologies and treatment approaches, chronic paronychia should be considered a separate entity from acute paronychia, which is the focus of this article. Another important differential diagnosis is herpetic whitlow, a herpes simplex virus infection that may manifest clinically with the presence of blisters involving the distal phalanx. Surgical drainage is contraindicated unless a concurrent bacterial infection is present. Paronychia involving toes is a relatively common condition and may be associated with ingrowing toenails. Although treatment approaches may be similar, the focus of this article is the management of acute paronychia drainage of the hand. Acute paronychia is diagnosed clinically with pain, swelling, and erythema of the nail folds. Formation of pus along the paronychial fold may occur; if untreated, an abscess may progress to involve the eponychium and the area below the nail plate. This can generally be identified by the presence of a tender, boggy swelling. As described by Turkmen et al., the digital pressure test can also be used to evaluate the presence of pus within the soft tissue. If light pressure is applied to the volar aspect of the tip of the affected digit, a localized region of skin blanching around the nail may indicate the presence of an underlying abscess. Furthermore, if pus is deep to the nail plate, it may be visible on inspection and ballotable on palpation. A felon is an infection in the pulp of the distal phalanx of a digit and is a separate condition from paronychia. Although a paronychia can lead to the development of a felon, the presence of one does not indicate the presence of the other. Careful examination of the digit should be performed to identify the clinical presence of a felon and thus the need for surgical drainage. This is characterized by a tender, fluctuant swelling involving the pulp of the digit. This article will only discuss acute paronychia drainage. In the early stage of paronychia, inflammation of the paronychial fold alone may be present, without pus formation. The majority of such cases may be managed non-operatively in the primary care or emergency department setting. Treatment involving oral antibiotics with close monitoring comprising follow-up appointments and patient safety advice is recommended. Oral antibiotics with gram-positive coverage are advised, or if suspecting exposure to oral bacteria, a broad-spectrum agent is preferable. Although some authors recommend using antiseptic or warm water soaks, there is no clear evidence to recommend their use routinely in any stage of the condition. In the later stage of paronychia, the presence of pus in the form of a local abscess may be present. Laboratory and radiological investigations are important in this stage. Plain film radiographs of the involved digit are used to investigate the possibility of associated foreign bodies, fractures, or osteomyelitis. Glucose testing is important to review glycemic control in patients with diabetes and may occasionally identify undiagnosed diabetes. Extended laboratory blood tests such as full blood count and inflammatory markers are generally only indicated in more severe cases where marked cellulitis or tracking lymphangitis is present. In all cases of paronychia with abscesses, surgical drainage is indicated. This may be performed in primary care or emergency department settings depending on local resources and expertise. Referral to tertiary hand surgery may otherwise be required.
急性甲沟炎是手部最常见的感染之一。它通常是由于甲板与甲襞之间的密封破坏,随后细菌或真菌病原体接种导致感染。这通常由咬指甲、外伤、修甲、嵌甲和倒刺处理引发。指甲周围软组织内出现脓肿,表明需要进行手术引流。从微生物学角度来看,手部甲沟炎据报道是一种多微生物感染,约50%的病例存在需氧菌和厌氧菌混合菌群。最常见的感染病原体是金黄色葡萄球菌(包括耐甲氧西林金黄色葡萄球菌(MRSA)),但其他需氧菌可能包括链球菌属或革兰氏阴性菌。而厌氧菌如丙酸杆菌属、消化链球菌属与通过咬指甲和吮指行为(在儿童中更常见)接触口腔分泌物有关。临床病史和局部抗生素指导,包括考虑MRSA感染率,应指导抗生素的处方。非细菌性感染较少见,但可能包括真菌感染如白色念珠菌,以及病毒感染如单纯疱疹。如果甲沟炎存在时间少于六周,则分类为急性,而存在六周或更长时间的则分类为慢性。慢性甲沟炎是一种多因素炎症性疾病,主要由接触环境过敏原或刺激物引起。这种炎症过程对保护屏障的破坏可能导致细菌或真菌定植。念珠菌是最常涉及的微生物。由于病因和治疗方法不同,慢性甲沟炎应被视为与急性甲沟炎不同的疾病,本文重点关注急性甲沟炎。另一个重要的鉴别诊断是疱疹性瘭疽,一种单纯疱疹病毒感染,临床上可能表现为涉及远端指骨的水疱。除非同时存在细菌感染,否则禁忌手术引流。涉及脚趾的甲沟炎是一种相对常见的情况,可能与嵌甲有关。虽然治疗方法可能相似,但本文重点是手部急性甲沟炎的处理。急性甲沟炎通过甲襞的疼痛、肿胀和红斑进行临床诊断。沿甲沟皱襞可能形成脓液;如果不治疗,脓肿可能进展至累及甲上皮和甲板下方区域。这通常可通过触痛、质地松软的肿胀来识别。如土库曼等人所述,指压试验也可用于评估软组织内是否有脓液。如果对患指指尖掌侧施加轻压,指甲周围局部皮肤变白可能表明存在潜在脓肿。此外,如果脓液在甲板下方较深位置,检查时可能可见,触诊时有波动感。脓性指头炎是手指远端指腹的感染,是与甲沟炎不同的疾病。虽然甲沟炎可导致脓性指头炎,但一种疾病的存在并不意味着另一种疾病也存在。应仔细检查手指以确定脓性指头炎的临床存在,从而确定是否需要手术引流。其特征为涉及指腹的触痛、波动感肿胀。本文仅讨论急性甲沟炎的引流。在甲沟炎早期,可能仅存在甲沟皱襞炎症,无脓液形成。大多数此类病例可在初级保健或急诊科非手术处理。建议使用覆盖革兰氏阳性菌的口服抗生素,并密切监测,包括随访预约和患者安全建议。建议使用覆盖革兰氏阳性菌的口服抗生素,或者如果怀疑接触口腔细菌,则使用广谱药物更佳。虽然一些作者建议使用防腐剂或温水浸泡,但没有明确证据推荐在该疾病的任何阶段常规使用。在甲沟炎后期,可能会出现局部脓肿形式的脓液。此阶段实验室和影像学检查很重要。受累手指的X线平片用于检查是否存在相关异物、骨折或骨髓炎。血糖检测对于评估糖尿病患者的血糖控制很重要,偶尔还可发现未诊断的糖尿病。扩展的实验室血液检查如全血细胞计数和炎症标志物一般仅在存在明显蜂窝织炎或淋巴管炎的更严重病例中进行。在所有甲沟炎伴脓肿的病例中,均需进行手术引流。这可根据当地资源和专业知识在初级保健或急诊科进行。否则可能需要转诊至三级手部外科。