General and Biological Psychology, University of Wuppertal, Germany.
General and Biological Psychology, University of Wuppertal, Germany.
Neurosci Lett. 2020 Sep 14;735:135236. doi: 10.1016/j.neulet.2020.135236. Epub 2020 Jul 6.
Recent applications of computationally calculated word co-occurrences allowed the prediction of left inferior frontal gyrus (LIFG) activation during semantic word processing. Hence, an interactive activation model, the associative read-out model (AROM), utilizes co-occurrences in its semantic processing layer and proposes connectivity from the LIFG along the ventral visual stream. Direct empirical evidence for its connectivity assumptions is so far missing, however. In this study, we employed psychophysiological interaction analysis on the neuroimaging data of a semantic priming experiment, targeting the LIFG as main region to resolve semantic conflicts. We further manipulated the prime and target word by co-occurrence-based direct association and semantic similarity in a full-factorial design. At a low semantic similarity, we observed increased functional connectivity of the LIFG to the fusiform gyrus, the hippocampus, the anterior cingulate cortex and the orbitofrontal cortex, indicating a connective pattern analogous to the semantic layer of the AROM. Surprisingly, a low (compared to a high) direct association showed no difference in brain activation, which raises the question about the diverging cognitive processes of the two priming types.
最近，基于计算得出的词汇共现的应用允许预测语义词汇处理过程中左侧额下回（LIFG）的激活。因此，一种交互激活模型，即联想读出模型（AROM），在其语义处理层中利用共现，并提出从 LIFG 沿着腹侧视觉流的连接。然而，到目前为止，还没有直接的经验证据支持其连接假设。在这项研究中，我们针对作为主要区域的 LIFG ，采用了语义启动实验的神经影像学数据的心理生理交互分析，以解决语义冲突。我们进一步通过共现直接关联和语义相似性在全因子设计中操纵启动词和目标词。在低语义相似性下，我们观察到 LIFG 与梭状回、海马体、前扣带皮层和眶额皮层的功能连接增加，表明连接模式类似于 AROM 的语义层。令人惊讶的是，低（与高相比）直接关联在大脑激活方面没有差异，这引发了关于两种启动类型的不同认知过程的问题。
