J Infect. 1988 Jul;17(1):71-82. doi: 10.1016/s0163-4453(88)92404-8.
Up to 31 December 1987, 1227 cases meeting the World Health Organization Centers for Disease Control (U.S.A.) (WHO/CDC) definition of the acquired immune deficiency syndrome (AIDS) were reported in the U.K., of which 54 were in persons who came to the U.K. for diagnosis and treatment and 1173 in U.K. residents. In the same period there were 8003 laboratory reports of human immunodeficiency virus (HIV) antibody-positive tests. The upward trend in the number of AIDS cases by quarter changed in the last quarter of 1987, when there were only 163 new reports. Predictions were revised so that 1450 new reports are expected in 1988. During a temporary increase in the number of tests performed in the first quarter of 1987, associated with a publicity campaign, the testing threshold for members of the homosexual/bisexual male risk group fell. The proportion of HIV antibody positive homosexual/bisexual men who were ill when tested in 1985 was between 50 and 73 each quarter; after 1985, this proportion has varied between 38 and 49%. The concentration of AIDS cases in the four Thames regions was marked, whereas HIV antibody-positive reports were more widely distributed. Since 1985, the proportion of the total HIV antibody-positive reports from the Thames-regions increased from less than a half to two-thirds. Among HIV antibody-positive women, over half were IV drug abusers and over two-thirds were in the age group 15-29 years. There were 19 cases of AIDS in children aged 14 years or less, eight of which were in visitors to the U.K. Of the 11 cases in U.K. residents, seven were in children of mothers known to have, or to be at risk of, HIV infection. The distribution of the 253 HIV antibody-positive reports in children was different; most were in haemophiliacs or blood/components recipients aged 5-14 years. Most mothers who have infected their children in utero were either IV drug abusers or sexual partners of IV drug abusers. Lymphoid interstitial pneumonia was the commonest indicator disease at the time of diagnosing AIDS in children. The mean age at diagnosis was 2 years 4 months for those infected in utero and 3 years 7 months for those otherwise infected. Between 1985 and 1987 there were marked increases of children with AIDS, of HIV antibody-positive children of infected/at-risk mothers and of reported HIV infections in women of child-bearing age. In the near future it is likely that many more pregnancies, particularly in Scotland, will be complicated by HIV infection.
截至1987年12月31日，英国共报告了1227例符合世界卫生组织美国疾病控制中心（WHO/CDC）获得性免疫缺陷综合征（AIDS）定义的病例，其中54例是来英国诊断和治疗的患者，1173例是英国居民。同一时期，有8003份人类免疫缺陷病毒（HIV）抗体检测呈阳性的实验室报告。艾滋病病例数按季度的上升趋势在1987年最后一个季度有所变化，当时仅有163份新报告。预测数据进行了修订，预计1988年将有1450份新报告。1987年第一季度，受一场宣传活动影响，检测数量暂时增加，同性恋/双性恋男性风险群体的检测门槛降低。1985年每个季度接受检测时患病的HIV抗体阳性同性恋/双性恋男性比例在50%至73%之间；1985年之后，这一比例在38%至49%之间波动。艾滋病病例在泰晤士河地区的四个区域集中情况明显，而HIV抗体阳性报告分布更为广泛。自1985年以来，泰晤士河地区的HIV抗体阳性报告在总数中的占比从不到一半增至三分之二。在HIV抗体阳性女性中，超过半数是静脉注射吸毒者，超过三分之二年龄在15至29岁之间。14岁及以下儿童中有19例艾滋病病例，其中8例是来英国的访客。在英国居民中的11例病例中，7例是已知感染HIV或有感染风险的母亲的孩子。253份儿童HIV抗体阳性报告的分布情况不同；大多数是5至14岁的血友病患者或血液/血液成分接受者。大多数在子宫内感染孩子的母亲要么是静脉注射吸毒者，要么是静脉注射吸毒者的性伴侣。淋巴样间质性肺炎是儿童诊断艾滋病时最常见的指示疾病。子宫内感染的儿童诊断时的平均年龄为2岁4个月，其他感染途径的儿童为3岁7个月。1985年至1987年期间，患艾滋病的儿童、感染/有感染风险母亲的HIV抗体阳性儿童以及育龄妇女报告的HIV感染病例数均显著增加。在不久的将来，很可能会有更多的妊娠，尤其是在苏格兰，会因HIV感染而出现并发症。
