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Upfront Daratumumab With Lenalidomide and Dexamethasone for POEMS Syndrome.达雷妥尤单抗联合来那度胺和地塞米松一线治疗POEMS综合征
Hemasphere. 2020 May 21;4(3):e381. doi: 10.1097/HS9.0000000000000381. eCollection 2020 Jun.
2
[Treatment of POEMS syndrome with lenalidomide and dexamethasone].来那度胺与地塞米松治疗POEMS综合征
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[Successful treatment of POEMS syndrome-associated pulmonary hypertension with lenalidomide and dexamethasone therapy].[来那度胺与地塞米松联合治疗POEMS综合征相关肺动脉高压取得成功]
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Daratumumab plus lenalidomide and dexamethasone lenalidomide and dexamethasone in relapsed or refractory multiple myeloma: updated analysis of POLLUX.达雷妥尤单抗联合来那度胺和地塞米松 vs. 来那度胺和地塞米松治疗复发或难治性多发性骨髓瘤：POLLUX 更新分析。
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Lenalidomide Treatment for Thalidomide-refractory POEMS Syndrome: A Prospective Single-arm Clinical Trial.来那度胺治疗沙利度胺难治性POEMS综合征：一项前瞻性单臂临床试验。
Intern Med. 2020 May 1;59(9):1149-1153. doi: 10.2169/internalmedicine.3800-19. Epub 2020 Feb 1.
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Improvement of thyroid function in POEMS syndrome after combination therapy of lenalidomide and dexamethasone.来那度胺联合地塞米松治疗后 POEMS 综合征患者甲状腺功能改善。
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Lenalidomide and dexamethasone in patients with POEMS syndrome: results of a prospective, open-label trial.来那度胺与地塞米松治疗POEMS综合征患者：一项前瞻性、开放标签试验的结果
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Efficacy and safety of low-dose lenalidomide plus dexamethasone in patients with relapsed or refractory POEMS syndrome.低剂量来那度胺联合地塞米松治疗复发或难治性POEMS综合征患者的疗效与安全性。
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A prospective phase II study of low dose lenalidomide plus dexamethasone in patients with newly diagnosed polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes (POEMS) syndrome.一项前瞻性 II 期研究，评估低剂量来那度胺联合地塞米松治疗新诊断的多发性神经病、器官肿大、内分泌病、单克隆丙种球蛋白病和皮肤改变（POEMS）综合征患者的疗效。
Am J Hematol. 2018 Jun;93(6):803-809. doi: 10.1002/ajh.25100. Epub 2018 Apr 18.

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Zhonghua Xue Ye Xue Za Zhi. 2025 May 14;46(5):389-396. doi: 10.3760/cma.j.cn121090-20241219-00578.
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EJHaem. 2024 Mar 30;5(2):421-422. doi: 10.1002/jha2.883. eCollection 2024 Apr.
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Daratumumab plus lenalidomide and dexamethasone for relapsed POEMS syndrome with bone plasmacytoma harboring 17p deletion.达雷妥尤单抗联合来那度胺和地塞米松治疗伴有17p缺失的骨浆细胞瘤复发的POEMS综合征
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Successful treatment with daratumumab, lenalidomide, and dexamethasone therapy followed by autologous stem cell transplantation for newly diagnosed polyneuropathy, organomegaly, endocrinopathy, M-protein, skin changes syndrome: a case report.采用达雷妥尤单抗、来那度胺和地塞米松联合治疗，随后进行自体造血干细胞移植治疗新诊断的多发性神经病、器官肿大、内分泌病、M 蛋白、皮肤改变综合征：一例报告。
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1
Daratumumab plus Lenalidomide and Dexamethasone for Untreated Myeloma.达雷妥尤单抗联合来那度胺和地塞米松治疗初治多发性骨髓瘤。
N Engl J Med. 2019 May 30;380(22):2104-2115. doi: 10.1056/NEJMoa1817249.
2
Daratumumab plus lenalidomide and dexamethasone lenalidomide and dexamethasone in relapsed or refractory multiple myeloma: updated analysis of POLLUX.达雷妥尤单抗联合来那度胺和地塞米松 vs. 来那度胺和地塞米松治疗复发或难治性多发性骨髓瘤：POLLUX 更新分析。
Haematologica. 2018 Dec;103(12):2088-2096. doi: 10.3324/haematol.2018.194282. Epub 2018 Sep 20.
3
European myeloma network recommendations on diagnosis and management of patients with rare plasma cell dyscrasias.欧洲骨髓瘤网络关于罕见浆细胞异常患者的诊断和管理的建议。
Leukemia. 2018 Sep;32(9):1883-1898. doi: 10.1038/s41375-018-0209-7. Epub 2018 Jul 23.
4
Daratumumab for POEMS Syndrome.达雷妥尤单抗治疗POEMS综合征
Mayo Clin Proc. 2018 Apr;93(4):542-544. doi: 10.1016/j.mayocp.2018.02.001.
5
POEMS syndrome: 2017 Update on diagnosis, risk stratification, and management.POEMS 综合征：2017 年关于诊断、风险分层和管理的更新。
Am J Hematol. 2017 Aug;92(8):814-829. doi: 10.1002/ajh.24802.
6
Daratumumab, Lenalidomide, and Dexamethasone for Multiple Myeloma.达雷妥尤单抗、来那度胺和地塞米松治疗多发性骨髓瘤。
N Engl J Med. 2016 Oct 6;375(14):1319-1331. doi: 10.1056/NEJMoa1607751.
7
Lenalidomide in patients with POEMS syndrome: a systematic review and pooled analysis.来那度胺治疗POEMS综合征患者：一项系统评价与汇总分析
Leuk Lymphoma. 2014 Sep;55(9):2018-23. doi: 10.3109/10428194.2013.869329. Epub 2014 Feb 17.
8
Efficacy of lenalidomide in POEMS syndrome: a retrospective study of 20 patients.来那度胺治疗 POEMS 综合征的疗效：20 例患者的回顾性研究。
Am J Hematol. 2013 Mar;88(3):207-12. doi: 10.1002/ajh.23374. Epub 2013 Jan 18.
9
Efficacy of lenalidomide plus dexamethasone for POEMS syndrome relapsed after autologous peripheral stem-cell transplantation.来那度胺联合地塞米松治疗自体外周血干细胞移植后复发的 POEMS 综合征的疗效。
Am J Hematol. 2012 Jun;87(6):641-2. doi: 10.1002/ajh.23195. Epub 2012 Apr 10.
10
Lenalidomide therapy in a patient with POEMS syndrome.来那度胺治疗POEMS综合征患者。
Blood. 2007 Aug 1;110(3):1075-6. doi: 10.1182/blood-2007-03-082354.

Upfront Daratumumab With Lenalidomide and Dexamethasone for POEMS Syndrome.

作者信息

Gavriatopoulou Maria, Ntanasis-Stathopoulos Ioannis, Fotiou Despina, Migkou Magdalini, Eleutherakis-Papaiakovou Evangelos, Kanellias Nikolaos, Roussou Maria, Dialoupi Ioanna, Malandrakis Panagiotis, Theodorakakou Foteini, Kastritis Efstathios, Terpos Evangelos, Dimopoulos Meletios-Athanasios

机构信息

Department of Clinical Therapeutics, National and Kapodistrian University of Athens, School of Medicine, Alexandra General Hospital, Athens, Greece.

出版信息

Hemasphere. 2020 May 21;4(3):e381. doi: 10.1097/HS9.0000000000000381. eCollection 2020 Jun.

DOI:10.1097/HS9.0000000000000381
PMID:32647800
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7306302/
Abstract
摘要