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COVID-19 的肺外并发症:一种多系统疾病?

Extrapulmonary complications of COVID-19: A multisystem disease?

机构信息

MAFLD Research Center, Department of Hepatology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.

Xi'an Medical University, Xi'an, China.

出版信息

J Med Virol. 2021 Jan;93(1):323-335. doi: 10.1002/jmv.26294. Epub 2020 Jul 22.

DOI:10.1002/jmv.26294
PMID:32648973
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7405144/
Abstract

The outbreak of coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has been recently declared a pandemic by the World Health Organization. In addition to its acute respiratory manifestations, SARS-CoV-2 may also adversely affect other organ systems. To date, however, there is a very limited understanding of the extent and management of COVID-19-related conditions outside of the pulmonary system. This narrative review provides an overview of the current literature about the extrapulmonary manifestations of COVID-19 that may affect the urinary, cardiovascular, gastrointestinal, hematological, hematopoietic, neurological, or reproductive systems. This review also describes the current understanding of the extrapulmonary complications caused by COVID-19 to improve the management and prognosis of patients with COVID-19.

摘要

2019 年冠状病毒病(COVID-19)的爆发是由严重急性呼吸系统综合征冠状病毒 2(SARS-CoV-2)引起的,世界卫生组织最近已宣布其为大流行。除了急性呼吸道表现外,SARS-CoV-2 还可能对其他器官系统产生不利影响。然而,迄今为止,对于肺外系统中与 COVID-19 相关的病症的程度和管理,人们的了解非常有限。这篇综述性文章概述了目前关于 COVID-19 的肺外表现的文献,这些表现可能会影响泌尿系统、心血管系统、胃肠道系统、血液系统、造血系统、神经系统或生殖系统。本文还描述了目前对 COVID-19 引起的肺外并发症的理解,以改善 COVID-19 患者的管理和预后。

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2
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Front Med (Lausanne). 2021 Jan 13;7:563893. doi: 10.3389/fmed.2020.563893. eCollection 2020.
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ACE2: A Linkage for the Interplay Between COVID-19 and Decompensated Cirrhosis.血管紧张素转换酶2:2019冠状病毒病与失代偿期肝硬化相互作用的一个关联因素
Am J Gastroenterol. 2020 Sep;115(9):1544. doi: 10.14309/ajg.0000000000000780.
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Liver Int. 2020 Sep;40(9):2160-2163. doi: 10.1111/liv.14575. Epub 2020 Jul 5.
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Coronavirus breakthrough: dexamethasone is first drug shown to save lives.冠状病毒研究突破:地塞米松是首个被证明能挽救生命的药物。
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