Department of Orthopedic Surgery, Resident Physician NYU Langone Medical Center, New York, New York.
Division of Orthopedic Oncology, Department of Orthopedic Surgery, NYU Langone Medical Center, New York, New York.
JBJS Case Connect. 2020 Apr-Jun;10(2):e0107. doi: 10.2106/JBJS.CC.19.00107.
A 72-year-old man presented for evaluation of bony prominences over extremities. Radiographic imaging demonstrated masses of varying sizes extending from the cortical surfaces without medullary continuity. The patient had a history of Freon inhalation abuse and was diagnosed with skeletal fluorosis due to elevated serum fluoride levels. He underwent an uncomplicated excision of a left fibular mass that was threatening skin breakdown.
This is the first reported surgical case of skeletal fluorosis demonstrating continued enlargement of bony prominences throughout the body. Skeletal fluorosis not only causes diffuse mineralization but may also lead to protruding lesions throughout the body.
一名 72 岁男性因四肢骨突起就诊。影像学检查显示，大小不一的肿块从皮质表面延伸，无髓质连续性。该患者有氟利昂吸入滥用史，由于血清氟化物水平升高而被诊断为氟骨症。他成功接受了左侧腓骨肿块的简单切除术，该肿块有皮肤破裂的危险。
这是首例报道的氟骨症外科病例，显示全身骨突起持续增大。氟骨症不仅导致弥漫性矿化，还可能导致全身突出性病变。
