Turner P, Volans G N, Rogers H J
Curr Med Res Opin. 1977;4(8):596-601. doi: 10.1185/03007997709115276.
A controlled, single-blind trial was carried out in 10 hypertensive patients to compare the effectiveness of a single daily dose (2.5 mg to 5 mg) of indapamide with that of placebo. Blood pressure was measured with a bias-free sphygmomanometer. Indapamide produced a significant reduction in mean systolic and diastolic pressures in both supine and erect positions. It was generally well tolerated: few side-effects were reported and no significant changes were noted in laboratory tests. It is concluded that further long-term studies of indapamide are indicated in larger numbers of patients.
对10名高血压患者进行了一项对照单盲试验，以比较每日单次剂量（2.5毫克至5毫克）的吲达帕胺与安慰剂的疗效。使用无偏差血压计测量血压。吲达帕胺使仰卧位和直立位的平均收缩压和舒张压均显著降低。它通常耐受性良好：报告的副作用很少，实验室检查未发现显著变化。结论是，需要对更多患者进行吲达帕胺的进一步长期研究。
