Egger M D, Bishop J W, Cone C H
Brain Res. 1976 Feb 20;103(2):215-28. doi: 10.1016/0006-8993(76)90795-2.
The plantar cushion reflex in cats was examined as a model system in a mammal for the study of the effects of repeated stimulation on neural transmission. Effects of various frequencies and intensities of stimulation were similar to those seen in other reflex systems. For instance, for a fixed number of stimuli, habituation of the plantar cushion reflex was more marked at 10 Hz than at 2.0 Hz, and with 1.0 X threshold stimulation than with 5.0 X threshold stimulation. Sensitization occurred at intermediate intensities and frequencies of stimulation. Dorsal root potentials were studied; changes in dorsal root potentials during iterated stimulation did not correlate with the changes in the plantar cushion reflex. These changes in the plantar cushion reflex were also unrelated to variations in afferent transmission peripheral to the spinal cord. Sensitization and habituation in the plantar cushion reflex occurred during iterated stimulation, were produced centrally, and were unrelated to mechanisms of presynaptic inhibition.
在猫身上对足底垫反射进行了研究，将其作为一种哺乳动物的模型系统，用于研究重复刺激对神经传递的影响。不同频率和强度刺激的效果与其他反射系统中观察到的相似。例如，对于固定数量的刺激，足底垫反射在10赫兹时比在2.0赫兹时更明显地出现习惯化，并且在1.0倍阈值刺激下比在5.0倍阈值刺激下更明显。在中等强度和频率的刺激下会出现敏感化。对背根电位进行了研究；重复刺激期间背根电位的变化与足底垫反射的变化不相关。足底垫反射的这些变化也与脊髓外周传入传递的变化无关。足底垫反射中的敏感化和习惯化在重复刺激期间发生，是在中枢产生的，并且与突触前抑制机制无关。
