一种用于活细胞中硝酰基成像的近红外荧光探针。
A near-infrared fluorescent probe for imaging of nitroxyl in living cells.
作者信息
Liu Zhipeng, Sun Qian
机构信息
College of Materials Science and Engineering, Nanjing Forestry University, 159 Longpan Road, Nanjing 210037, China.
College of Materials Science and Engineering, Nanjing Forestry University, 159 Longpan Road, Nanjing 210037, China.
出版信息
Spectrochim Acta A Mol Biomol Spectrosc. 2020 Nov 5;241:118680. doi: 10.1016/j.saa.2020.118680. Epub 2020 Jul 3.
A BODIPY-based NIR fluorescent probe, NitroxylBDP, for the rapid and specific, detection of HNO has been designed and synthesized. The merits of NIR fluorescence, and stable fluorescence output against pH changes, and good membrane permeability, enable the probe to serve as an ideal indicator for tracking HNO in living systems.
一种基于BODIPY的近红外荧光探针NitroxylBDP已被设计并合成，用于快速、特异性地检测一氧化氮（HNO）。近红外荧光、对pH变化稳定的荧光输出以及良好的膜通透性等优点，使该探针成为在生物系统中追踪HNO的理想指示剂。
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