Department of Surgery, Tehran University of Medical Sciences, Tehran, Iran; Department of Surgical Oncology, University of Montreal, Montreal, Canada.
Department of Surgery, Tehran University of Medical Sciences, Tehran, Iran.
Clin Breast Cancer. 2020 Dec;20(6):511-519. doi: 10.1016/j.clbc.2020.05.016. Epub 2020 Jun 7.
Breast-conserving surgery, especially with oncoplastic breast surgery (OBS), is becoming the standard of care in the surgical management of breast cancer. We investigated the applied technique of OBS and oncologic outcomes in a large series of patients.
This study was conducted between January 2008 and June 2018 in two centers in Iran. Patients underwent OBS. Early and late postoperative complications, oncologic outcomes, and follow-up data were documented.
Nine hundred thirty-seven patients with a mean ± standard deviation age of 48.1 ± 11.3 underwent OBS. Most of the patients were diagnosed with early-stage disease, of which the most common pathology was invasive ductal carcinoma (83.3%). Lateral oncoplasty was the most commonly used OBS technique (324 cases, 34.6%). The most common complication was seroma formation. Reduction-type OBS technique had the highest rate of complications (13.1%). Thirty-four patients (5.4%) experienced local recurrence, with a median recurrence time of 26.4 months. Nine patients (1.3%) died from cancer recurrence.
OBS is a safe procedure with minor complications and good oncologic outcomes. These techniques can be applied to most patients who are candidates for breast-conserving surgery.
保乳手术，特别是肿瘤整形保乳术（OBS），在乳腺癌的外科治疗中已成为标准治疗方法。我们在一系列大量患者中研究了 OBS 的应用技术和肿瘤学结果。
这项研究于 2008 年 1 月至 2018 年 6 月在伊朗的两个中心进行。患者接受了 OBS。记录了早期和晚期术后并发症、肿瘤学结果和随访数据。
937 名平均年龄为 48.1 ± 11.3 岁的患者接受了 OBS。大多数患者被诊断为早期疾病，其中最常见的病理学是浸润性导管癌（83.3%）。侧向肿瘤整形术是最常用的 OBS 技术（324 例，34.6%）。最常见的并发症是血清肿形成。减少型 OBS 技术的并发症发生率最高（13.1%）。34 名患者（5.4%）经历了局部复发，中位复发时间为 26.4 个月。9 名患者（1.3%）死于癌症复发。
OBS 是一种安全的手术，并发症较少，肿瘤学结果良好。这些技术适用于大多数适合保乳手术的患者。
