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先天性上睑下垂术后睑裂闭合不全:提上睑肌切除术与额肌悬吊术的比较。

Lagophthalmos after congenital ptosis surgery: comparison between maximal levator resection and frontalis sling operation.

机构信息

Ophthalmic Plastic and Reconstructive Surgery, Eagle Eye Centre, Singapore, Singapore.

Department of Ophthalmology, Osaka Kaisei Hospital, Osaka, Japan.

出版信息

Eye (Lond). 2021 Apr;35(4):1261-1267. doi: 10.1038/s41433-020-1081-z. Epub 2020 Jul 10.

Abstract

BACKGROUND/OBJECTIVES: To compare postoperative lagophthalmos after maximal levator resection (MLR) and frontalis suspension (FS) in congenital ptosis patients with poor levator function (LF).

METHODS

A cross-sectional study was performed to compare postoperative outcomes in patients with preoperative LF ≤ 4 mm who had undergone MLR or FS at a single tertiary institution, and who had visited the outpatient clinic between February 2017 and August 2018. Main outcome measures were as follows: (1) Preoperative LF and margin reflex distance 1 (MRD1), (2) Postoperative MRD1, lagophthalmos and grade of superficial punctate keratopathy (SPK).

RESULTS

Our study comprised 152 eyelids of 122 patients. There were 71 eyelids in the MLR group and 81 eyelids in the FS group. The MLR group had comparable mean postoperative MRD1 (2.8 ± 0.8 mm) to the FS with autogenous fascia lata (AFL) group (3.0 ± 0.7 mm), while the FS with preserved fascia lata (PFL) group had the lowest mean postoperative MRD1 (2.2 ± 1.0 mm). The PFL group had significantly less lagophthalmos (0.6 ± 1.0 mm) than the AFL (1.9 ± 1.4 mm) and maximal levator resection (1.9 ± 1.7 mm) groups. In the MLR group, there was no significant difference in postoperative surgical measurements between the LF 0-2 mm group and LF 2.5-4 mm group in terms of exposure keratopathy, degree of lagophthalmos and MRD1.

CONCLUSION

MLR is an effective alternative to FS in congenital ptosis patients with poor levator function, with the risk of postoperative lagophthalmos related to postoperative MRD1 rather than preoperative LF.

摘要

背景/目的:比较重度提上睑肌切除术(MLR)和额肌悬吊术(FS)治疗提上睑肌功能不良(LF)的先天性上睑下垂患者术后的睑裂闭合不全。

方法

本研究为单中心回顾性研究,比较了 2017 年 2 月至 2018 年 8 月在我院接受 MLR 或 FS 的术前 LF≤4mm 的先天性上睑下垂患者的术后结果。主要观察指标为:(1)术前 LF 和上睑缘至角膜映光点距离 1(MRD1);(2)术后 MRD1、睑裂闭合不全和浅层点状角膜病变(SPK)程度。

结果

共纳入 122 例患者的 152 只眼,其中 MLR 组 71 只眼,FS 联合自体阔筋膜组 81 只眼,FS 联合保留阔筋膜组 81 只眼。MLR 组术后平均 MRD1(2.8±0.8mm)与 FS 联合自体阔筋膜组(3.0±0.7mm)相当,FS 联合保留阔筋膜组术后平均 MRD1(2.2±1.0mm)最低。FS 联合保留阔筋膜组的睑裂闭合不全程度(0.6±1.0mm)明显轻于 FS 联合自体阔筋膜组(1.9±1.4mm)和 MLR 组(1.9±1.7mm)。在 MLR 组中,LF 为 0-2mm 和 LF 为 2.5-4mm 的患者术后暴露性角膜炎、睑裂闭合不全程度和 MRD1 差异均无统计学意义。

结论

对于提上睑肌功能不良的先天性上睑下垂患者,MLR 是 FS 的有效替代方法,术后睑裂闭合不全的风险与术后 MRD1 相关,而非术前 LF。

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