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一期后路手术治疗伴椎管内异常的特发性脊柱侧凸青少年患者的安全性和疗效:至少 3 年的随访比较研究。

The safety and efficacy of one-stage posterior surgery in the treatment of presumed adolescent idiopathic scoliosis associated with intraspinal abnormalities a minimum 3-year follow-up comparative study.

机构信息

Department of Orthopedics, Beijing Chaoyang Hospital, Capital Medical University, GongTiNanLu 8#, Chaoyang District, Beijing, 100020, China.

Department of Orthopedics, Shougang Hospital, Peking University, JinyuanzhuangLu 9#, Shijingshan District, Beijing, 100144, China.

出版信息

Eur Spine J. 2021 Mar;30(3):692-697. doi: 10.1007/s00586-020-06529-x. Epub 2020 Jul 10.

Abstract

PURPOSE

Adolescent idiopathic scoliosis (AIS) is a common type of idiopathic scoliosis. Previous studies reported that the incidence of intraspinal abnormalities among the presumed idiopathic scoliosis was 13-43%. Intraspinal abnormalities were also considered increasing the risks of progressing of scoliosis and neurological complications following scoliosis corrective surgery. The surgical strategy of presumed adolescent idiopathic scoliosis (PAIS) associated with intraspinal abnormalities remains controversial. The purpose of this study was to investigate whether one-stage posterior surgery safe and effective for the PAIS patients associated with intraspinal abnormalities.

MATERIALS AND METHODS

One hundred and thirteen consecutive patients who underwent one-stage posterior correction surgery were included. Thirty PAIS patients with intraspinal abnormalities without preoperative neurological symptoms were matched with eighty-three AIS patients for sex, age, blood loss, operating time, number of levels and location of instrumentation and curve magnitude. Radiographic and clinical parameters of the patients were evaluated before surgery, within 1 week after surgery, and more than 3 years at the last follow-up for complications and changes in main curve correction, global coronal balance, thoracic kyphosis, sagittal vertical axis, and ODI scores.

RESULTS

On average, the duration of follow-up was 51.5 months in the PAIS group compared to 52.5 months in the AIS group. The preoperative mean major coronal curve was 79.6° (ranged 56.2°-106.7°) and improved to 22.4° (ranged 6.4°-58.1°) at the last follow-up for a 71.9% of correction in the AIS group. The preoperative mean major coronal curve was 80.4° (ranged 63.4°-108.1°) and improved to 23.2° (ranged 4.8°-66.2°) at the last follow-up for a 71.1% of correction in PAIS group. The preoperative ODI score was 32.4 (10-42) in the PAIS group and improved to 11.4 (4-22) at last follow-up, 33.4 (12-42) in the AIS group and improved to 11.5 (5-22) at last follow-up. The global coronal balance, TK and SVA were all significantly improved after surgery and maintained to the last follow-up in the two groups. The neurological complications were observed in 3.3% of PAIS patients and 3.6% of AIS patients. No statistical difference in the parameters between the two groups was observed at the last follow-up.

CONCLUSION

One-stage posterior corrective surgery is safe and effective in PAIS patients associated with intraspinal abnormalities without preoperative neurological symptoms. Surgical guidelines of AIS are appropriate for the treatment of PAIS patients associated with intraspinal abnormalities.

摘要

目的

青少年特发性脊柱侧凸(AIS)是一种常见的特发性脊柱侧凸类型。先前的研究报告称,假定特发性脊柱侧凸中脊柱内异常的发生率为 13-43%。脊柱内异常也被认为增加了脊柱侧凸进展和脊柱侧凸矫正手术后神经并发症的风险。假定青少年特发性脊柱侧凸(PAIS)伴脊柱内异常的手术策略仍存在争议。本研究旨在探讨一期后路矫形手术是否对伴脊柱内异常的 PAIS 患者安全有效。

材料和方法

纳入了 113 例接受一期后路矫正手术的连续患者。30 例伴脊柱内异常且无术前神经症状的 PAIS 患者与 83 例 AIS 患者相匹配,比较性别、年龄、出血量、手术时间、器械的节段数和位置以及曲线大小。在术前、术后 1 周内和末次随访时对患者的影像学和临床参数进行评估,以评估主要曲线矫正、整体冠状平衡、胸椎后凸、矢状垂直轴和 ODI 评分的变化以及并发症。

结果

PAIS 组的平均随访时间为 51.5 个月,AIS 组为 52.5 个月。AIS 组术前平均主冠状曲线为 79.6°(56.2°-106.7°),末次随访时改善至 22.4°(6.4°-58.1°),矫正率为 71.9%。PAIS 组术前平均主冠状曲线为 80.4°(63.4°-108.1°),末次随访时改善至 23.2°(4.8°-66.2°),矫正率为 71.1%。PAIS 组术前 ODI 评分为 32.4(10-42),末次随访时改善至 11.4(4-22),AIS 组术前 ODI 评分为 33.4(12-42),末次随访时改善至 11.5(5-22)。两组术后均明显改善了冠状平衡、胸椎后凸和矢状垂直轴,且在末次随访时均保持稳定。PAIS 组有 3.3%的患者和 AIS 组有 3.6%的患者出现神经并发症。末次随访时,两组各参数无统计学差异。

结论

对于无术前神经症状的伴脊柱内异常的 PAIS 患者,一期后路矫正手术是安全有效的。AIS 的手术指南适用于伴脊柱内异常的 PAIS 患者的治疗。

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