Betz R R, Harms J, Clements D H, Lenke L G, Lowe T G, Shufflebarger H L, Jeszenszky D, Beele B
Shriners Hospital, Philadelphia, Pennsylvania, USA.
Spine (Phila Pa 1976). 1999 Feb 1;24(3):225-39. doi: 10.1097/00007632-199902010-00007.
This was a prospective study of two cohort groups of patients (one group receiving anterior instrumentation and the other posterior instrumentation) receiving treatment for thoracic idiopathic scoliosis.
To present the 2-year postoperative results of a prospective multicenter study comparing the use of anterior instrumentation with that of posterior multisegmented hook instrumentation for the correction of adolescent thoracic idiopathic scoliosis.
Despite reports of satisfactory results, problems have been reported with posterior systems, including worsening of the lumbar curve after surgery and failure to correct hypokyphosis. Theoretically, the advantages of anterior instrumentation include prevention of lumbar curve decompensation by shortening the convexity of the thoracic curve. In addition, by removing the disc, better correction of thoracic hypokyphosis could be obtained.
Seventy-eight patients who underwent an anterior spinal fusion using flexible threaded rods and nuts (Harms-MOSS instrumentation, De Puy-Motech-Acromed, Cleveland, OH) were analyzed and compared with 100 patients who underwent posterior spinal fusion with multisegmented hook systems. Parameters of comparison included coronal and sagittal correction, balance, distal lumbar fusion levels, and complication. All patients had idiopathic thoracic curves of King Types II to V. The average age at surgery was 14 years in each group, the average preoperative curve 57 degrees, and the minimum duration of follow-up for all patients 24 months. All data were collected prospectively and analyzed via Epl into statistical analysis (Centers of Disease Control, Atlanta, GA).
Average coronal correction of the main thoracic curve was 58% in the anterior group and 59% in the posterior group (P = 0.92). Analysis of sagittal contour showed that the posterior systems failed to correct a preoperative hypokyphosis (sagittal T5 to T12 less than 20 degrees) in 60% of cases, whereas 81% were normal postoperatively in the anterior group. However, hyperkyphosis (sagittal T5 to T12 greater than 40 degrees) occurred after surgery in 40% of the anterior group when the preoperative kyphosis was greater than 20 degrees. Postoperative coronal balance was equal in both groups. An average of 2.5 (range, 0-6) distal fusion levels were saved using the anterior spinal instrumentation according to the criteria used for determining posterior fusion levels in this study. Selective fusion of the thoracic curve (distal fusion level T11, T12, L1) was performed in 76 of 78 patients (97%) in the anterior group as compared with only 18 of 100 (18%) in the posterior group. Surgically confirmed pseudarthrosis occurred in 4 of 78 patients (5%) in the anterior group and in 1 of 100 patients (1%) in the posterior group (P = 0.10). Loss of correction greater than 10 degrees occurred in 18 of 78 patients (23%) in the anterior group and in 12 of 100 patients (12%) in the posterior group (P = 0.01). Implant breakage occurred in 24 patients (31%) of the anterior group and in only 1 patient (1%) of the posterior group.
这是一项针对两组接受胸椎特发性脊柱侧弯治疗患者的前瞻性研究(一组接受前路器械固定,另一组接受后路器械固定)。
呈现一项前瞻性多中心研究的术后2年结果,该研究比较了前路器械固定与后路多节段钩形器械固定在矫正青少年胸椎特发性脊柱侧弯中的应用。
尽管有报道称结果令人满意,但后路系统也存在一些问题,包括术后腰椎曲线恶化以及未能矫正后凸不足。理论上,前路器械固定的优点包括通过缩短胸弯凸侧来预防腰椎曲线失代偿。此外,通过切除椎间盘,可以更好地矫正胸椎后凸不足。
分析了78例行前路脊柱融合术并使用柔性螺纹杆和螺母(Harms-MOSS器械,De Puy-Motech-Acromed,俄亥俄州克利夫兰)的患者,并与100例行后路脊柱融合术并使用多节段钩形系统的患者进行比较。比较参数包括冠状面和矢状面矫正、平衡、远端腰椎融合节段以及并发症。所有患者均患有King II至V型特发性胸弯。每组患者手术时的平均年龄为14岁,术前平均弯曲度为57度,所有患者的最短随访时间为24个月。所有数据均前瞻性收集,并通过Epl进行统计分析(美国疾病控制中心,佐治亚州亚特兰大)。
前路组主胸弯的平均冠状面矫正率为58%,后路组为59%(P = 0.92)。矢状面轮廓分析显示,后路系统在60%的病例中未能矫正术前的后凸不足(矢状面T5至T12小于20度),而前路组术后81%的患者矢状面正常。然而,当术前后凸大于20度时,前路组40%的患者术后出现了后凸过大(矢状面T5至T12大于40度)。两组术后冠状面平衡相同。根据本研究中确定后路融合节段的标准,使用前路脊柱器械固定平均可节省2.5个(范围为0至6个)远端融合节段。前路组78例患者中有76例(97%)进行了胸弯的选择性融合(远端融合节段为T11、T12、L1),而后路组100例患者中只有18例(18%)进行了同样的融合。手术证实的假关节形成在前路组78例患者中有4例(5%),后路组100例患者中有1例(1%)(P = 0.10)。矫正丢失大于10度在前路组78例患者中有l8例(23%),后路组100例患者中有12例(12%)(P = 0.01)。前路组有24例患者(31%)发生了植入物断裂,而后路组只有1例患者(1%)发生了植入物断裂。
1)尽管前路组大多数曲线(97%)融合至L1或更短节段,而后路组只有18%融合至L1或更短节段,但前后路两组的冠状面矫正和平衡相同。2)在前路组中,术前后凸不足小于20度的患者矢状面轮廓矫正更好。然而,术前后凸大于20度的患者中,前路组40%出现了后凸过大(平均为54度)。3)根据本研究中选择后路融合节段的标准,前路融合和器械固定平均可节省2.5个腰椎节段。4)在本研究中使用3.2毫米柔性杆时,矫正丢失、假关节形成和杆断裂的发生率高得令人无法接受。