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肠侵袭性大肠埃希菌生物型 1B 病例报告:一种不常见的病原体引起的装置相关性骨关节感染。

Yersinia enterocolitica biotype 1B case report: an unusual pathogen in an osteoarticular infection on device.

机构信息

CHU Lille, F 59000, Lille, France.

Laboratoire de Bactériologie - Institut de Microbiologie, Centre de Biologie Pathologie, F-59037, Lille Cedex, France.

出版信息

BMC Infect Dis. 2020 Jul 11;20(1):498. doi: 10.1186/s12879-020-05204-2.

Abstract

BACKGROUND

Yersinia enterocolitica is an aero-anaerobic Gram-negative coccobacilli of the Enterobacteriaceae family, rarely reported in osteoarticular infection.

CASE PRESENTATION

This report case described a rare septic osteoarticular infection on device due to Yersinia enterocolitica biotype 1B. A purulent fistula appeared after osteosynthesis with plate performed abroad 27 days prior to the presentation for a distal femoral fracture. The treatment consisted of surgical irrigation and washing of the femoral plate and a bitherapy by levoflaxacine and ceftriaxone during 3 months.

CONCLUSION

Y. enterocolitica biotype 1B is extremely rare in France. Moreover, the strain implicated in this european case is extremely close from the USA reference strain (with only 2 SNP difference) described in a septicemia in Ohio. The extreme proximity of the strains underlines the need for a sustained surveillance of the spread of this pathogen in France.

摘要

背景

小肠结肠炎耶尔森菌是肠杆菌科的一种需氧兼性厌氧革兰阴性球杆菌,很少引起骨关节感染。

病例介绍

本报告描述了一例罕见的由小肠结肠炎耶尔森菌生物型 1B 引起的与植入物相关的化脓性骨关节感染。患者因股骨远端骨折在国外行钢板内固定术后 27 天出现脓性瘘管。治疗包括手术冲洗和清洗股骨钢板,并使用左氧氟沙星和头孢曲松进行双抗治疗 3 个月。

结论

小肠结肠炎耶尔森菌生物型 1B 在法国极为罕见。此外,该欧洲病例中涉及的菌株与美国俄亥俄州败血症中描述的参考菌株(仅相差 2 个 SNP)非常接近。菌株的高度接近强调了在法国持续监测这种病原体传播的必要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2254/7353708/6a731eceaeea/12879_2020_5204_Fig1_HTML.jpg

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