National Centre for Immunisation Research and Surveillance, Westmead, NSW, Australia; Department of Infectious Diseases, Nepean Hospital, Penrith, NSW, Australia.
National Centre for Immunisation Research and Surveillance, Westmead, NSW, Australia.
Paediatr Respir Rev. 2020 Sep;35:43-49. doi: 10.1016/j.prrv.2020.06.010. Epub 2020 Jun 18.
There is a strong consensus globally that a COVID-19 vaccine is likely the most effective approach to sustainably controlling the COVID-19 pandemic. An unprecedented research effort and global coordination has resulted in a rapid development of vaccine candidates and initiation of trials. Here, we review vaccine types, and progress with 10 vaccine candidates against SARS-CoV-2 - the virus that causes COVID-19 - currently undergoing early phase human trials. We also consider the many challenges of developing and deploying a new vaccine on a global scale, and recommend caution with respect to our expectations of the timeline that may be ahead.
全球范围内有一个强烈的共识，即 COVID-19 疫苗可能是可持续控制 COVID-19 大流行的最有效方法。前所未有的研究努力和全球协调导致了疫苗候选物的快速开发和试验启动。在这里，我们回顾了针对导致 COVID-19 的 SARS-CoV-2 病毒的 10 种疫苗候选物的类型和进展，这些候选物目前正在进行早期人体试验。我们还考虑了在全球范围内开发和部署新疫苗所面临的许多挑战，并对我们对未来可能出现的时间表的期望持谨慎态度。
