Abdollahi Fakhim Shahin, Nouri-Vaskeh Masoud, Amiri Faezeh, Shahidi Nikzad
Department of Otorhinolaryngology, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Oral Maxillofac Surg. 2020 Dec;24(4):495-499. doi: 10.1007/s10006-020-00884-1. Epub 2020 Jul 11.
Velopharyngeal failure occurs as a result of a nasopharyngeal gap following inadequate velopharyngeal closure for structural or functional cause. We aimed to compare the soft palate length in two-flap palatoplasty with intravelar veloplasty (IVV) and two-flap palatoplasty with IVV plus double-layer Z-plasty combination in patients with cleft palate.
This clinical trial was conducted on infants aged 9 to 12 months with cleft palate in two groups. The method of two-flap palatoplasty with IVV technique and two-flap palatoplasty with IVV plus double-layer Z-plasty was compared in terms of soft palate length which was measured during operation and short-term complications.
This study was conducted on 62 infants including 30 patients in two-flap palatoplasty with IVV group and 32 patients in two-flap palatoplasty with IVV plus double-layer Z-plasty group. The soft palate length in two-flap palatoplasty and IVV with and without Z-plasty groups before surgery was 17.56 ± 2.05 and 17.68 ± 1.88 mm, respectively (P = 0.561). After surgery, the soft palate length was significantly higher in two-flap palatoplasty with IVV plus Z-plasty group (22.43 ± 2.73 mm vs. 20.56 ± 2.42 mm) (P = 0.032).
The two-flap palatoplasty with IVV plus Z-plasty technique is a suitable method for increasing the palatal length in infants with cleft palate. On the other hand, the addition of Z-plasty method could increase the length of the palate. Moreover, the complications are very low and further trials for development of this method on patients with cleft palate are recommended.
TRIAL REGISTRATION NUMBER (TRN): IRCT2017032423559N11.
腭咽闭合不全是由于结构或功能原因导致腭咽闭合不足后出现鼻咽间隙所致。我们旨在比较腭裂患者中双瓣腭成形术联合腭内腭成形术（IVV）与双瓣腭成形术联合IVV加双层Z成形术联合治疗时的软腭长度。
本临床试验在两组9至12个月大的腭裂婴儿中进行。比较双瓣腭成形术联合IVV技术与双瓣腭成形术联合IVV加双层Z成形术在手术中测量的软腭长度及短期并发症方面的差异。
本研究共纳入62例婴儿，其中双瓣腭成形术联合IVV组30例，双瓣腭成形术联合IVV加双层Z成形术组32例。术前双瓣腭成形术联合IVV组和双瓣腭成形术联合IVV加双层Z成形术组的软腭长度分别为17.56±2.05和17.68±1.88mm（P = 0.561）。术后，双瓣腭成形术联合IVV加Z成形术组的软腭长度显著更高（22.43±2.73mm对20.56±2.42mm）（P = 0.032）。
双瓣腭成形术联合IVV加Z成形术是增加腭裂婴儿腭长度的合适方法。另一方面，增加Z成形术可增加腭的长度。此外，并发症非常低，建议对该方法在腭裂患者中的进一步发展进行试验。
试验注册号（TRN）：IRCT2017032423559N11。
