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富有同情心的胚胎移植:医生的实践和观点。

Compassionate embryo transfer: physician practices and perspectives.

机构信息

Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology and Infertility, Northwestern University Feinberg School of Medicine, Chicago, Illinois.

Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology and Infertility, Northwestern University Feinberg School of Medicine, Chicago, Illinois.

出版信息

Fertil Steril. 2020 Sep;114(3):552-557. doi: 10.1016/j.fertnstert.2020.04.026. Epub 2020 Jul 9.

Abstract

OBJECTIVE

To assess reproductive endocrinology and infertility (REI) physicians' basic knowledge of compassionate embryo transfer, current practices, and perceived barriers to offering compassionate transfer.

DESIGN

Cross-sectional survey study.

SETTING

Not applicable.

PATIENTS

Not applicable.

INTERVENTION

None.

MAIN OUTCOME MEASURES

Number of physicians offering and performing compassionate transfer, barriers, beliefs and demographics of physicians.

RESULTS

A total of 744 members of the Society for Reproductive Endocrinology and Infertility were sent the survey, and 202 (27.1%) responded. Of the 168 (83.2%) physicians who had heard of compassionate transfer, 75 (44.6%) had offered it. In all, 130 physicians stated that they would offer compassionate transfer if there was patient demand, and 74 would offer it if there were American Society for Reproductive Medicine guidelines. Among physicians who did not offer compassionate transfer, 97 cited lack of patient interest as a barrier. In all, 55 physicians had performed compassionate transfer (range 0-8) performed within the past 2 years. The majority of physicians (76.4%) placed embryos in the endometrium, and there was no consensus on timing. Of the physicians, 27 restricted the number of embryos transferred. Three physicians reported pregnancies following compassionate transfer; none were ectopic.

CONCLUSION

Data from this survey suggest that REI physicians have a wide range of knowledge and practices concerning compassionate transfer. Individual practices should be encouraged to develop written protocols regarding the use of embryos for nonreproductive purposes. American Society for Reproductive Medicine should develop recommendations to standardize the practice of compassionate transfer for those physicians who plan to offer this procedure.

摘要

目的

评估生殖内分泌学和不孕不育(REI)医师对同情胚胎转移的基本知识、当前实践以及提供同情性转移的感知障碍。

设计

横断面调查研究。

地点

不适用。

患者

不适用。

干预措施

无。

主要观察指标

提供和进行同情性转移的医师人数、障碍、医师的信念和人口统计学特征。

结果

向生殖内分泌学会的 744 名成员发送了调查,有 202 名(27.1%)做出了回应。在听说过同情性转移的 168 名(83.2%)医师中,有 75 名(44.6%)提供了该服务。共有 130 名医师表示,如果有患者需求,他们将提供同情性转移,如果有美国生殖医学学会的指南,他们将提供 74 次转移。在没有提供同情性转移的医师中,有 97 名表示缺乏患者兴趣是一个障碍。共有 55 名医师在过去 2 年内进行了同情性转移(范围 0-8)。大多数医师(76.4%)将胚胎放置在内膜中,并且在时间上没有共识。在这些医师中,有 27 名限制了转移的胚胎数量。有 3 名医师报告了同情性转移后的妊娠,但均非宫外孕。

结论

这项调查的数据表明,REI 医师对同情性转移有广泛的知识和实践。应鼓励个别实践制定有关将胚胎用于非生殖目的的书面方案。美国生殖医学学会应为计划提供此程序的医师制定同情性转移的标准实践建议。

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