依赖类固醇的肾病综合征患儿发热的罕见病因。
Uncommon cause of fever in a child with steroid-dependent nephrotic syndrome.
作者信息
Sethi Sidharth Kumar, Bansal Shyam, Chakraborty Ronith, Jain Rahul, Wadhwani Nikita, Raina Rupesh
机构信息
Kidney Institute, Medanta, The Medicity Hospital, Gurgaon, Haryana, India, and.
Akron General Medical Center, and.
出版信息
Clin Nephrol Case Stud. 2020 Jul 7;8:49-52. doi: 10.5414/CNCS110062. eCollection 2020.
BACKGROUND
Children with nephrotic syndrome are vulnerable to developing infections due to a state of relative immunodeficiency, malnourishment, and use of immunosuppression. Case characteristics: We herein report the case of a 3-year-old child with steroid-dependent nephrotic syndrome who presented to us with fever of unknown origin.
OBSERVATION
The child was found to have an atypical mixed infection with mycoplasma and cytomegalovirus.
OUTCOME
The infection completely resolved with appropriate treatment and lowering of immunosuppression. Message: Persistently febrile pediatric patients, especially in the setting of recent immunosuppression and absence of otherwise-identified infectious pathogens, should be screened for atypical mixed infections.
背景
肾病综合征患儿由于处于相对免疫缺陷、营养不良和使用免疫抑制状态，易发生感染。病例特征：我们在此报告一名3岁的类固醇依赖型肾病综合征患儿，因不明原因发热前来就诊。
观察结果
发现该患儿患有支原体和巨细胞病毒的非典型混合感染。
结果
通过适当治疗和降低免疫抑制，感染完全得到解决。启示：持续发热的儿科患者，尤其是近期有免疫抑制且未发现其他明确感染病原体的情况下，应筛查非典型混合感染。
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