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使用动脉球囊辅助的氰基丙烯酸正丁酯经静脉栓塞治疗动静脉畸形:确定经静脉治疗方法的参数,作为治疗脑动静脉畸形的一种潜在初始治疗选择。

N-Butyl Cyanoacrylate Transvenous Arteriovenous Malformation Embolization with Arterial Balloon Assistance: Defining Parameters for a Transvenous Approach as a Potential Upfront Treatment Option in Managing Cerebral Arteriovenous Malformations.

作者信息

Higbie Catherine, Khatri Deepak, Ligas Barbara, Ortiz Rafael, Langer David

机构信息

Department of Neurosurgery, Lenox Hill Hospital, New York City, New York, USA.

出版信息

Asian J Neurosurg. 2020 Apr 7;15(2):434-439. doi: 10.4103/ajns.AJNS_357_19. eCollection 2020 Apr-Jun.

DOI:10.4103/ajns.AJNS_357_19
PMID:32656149
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7335129/
Abstract

Complete obliteration of arteriovenous malformations (AVMs) using a transvenous approach as the primary and stand-alone treatment modality has been increasingly considered as a useful endovascular approach in the treatment of AVMs. AVMs are typically treated with microsurgery, stereotactic radiosurgery, endovascular embolization, or some combination of the three methods. Preservation of the draining vein is a key requisite common to all treatment modalities. Transvenous embolization (TVE) is conventionally not recommended as a stand-alone treatment for the vast majority of AVMs and has been thought to be best indicated when traditional approaches are considered less safe and when specific evaluation criteria are met. We report a case of a 35-year-old asymptomatic male diagnosed with a small intracranial AVM adjacent to the right motor strip which was managed utilizing this approach. We employed endovascular embolization via a transvenous approach with arterial balloon assistance due to the small size of the nidus, eloquent location, arterial supply proximal to the venous varix, and a single draining vein from the fistula. This case illustrates the selective indications and technical nuances of TVE approach in managing AVMs as a potential upfront treatment option. When patients harbor AVMs with specific angio-architectural findings as outlined, TVE utilizing Onyx or N-butyl cyanoacrylate can be safely performed as a primary treatment modality.

摘要

将经静脉途径作为主要的独立治疗方式完全闭塞动静脉畸形(AVM),越来越被认为是治疗AVM的一种有效的血管内治疗方法。AVM通常采用显微手术、立体定向放射外科、血管内栓塞或这三种方法的某种联合进行治疗。保留引流静脉是所有治疗方式共有的关键要求。传统上,经静脉栓塞(TVE)不被推荐作为绝大多数AVM的独立治疗方法,并且一直被认为在传统方法被认为不太安全且满足特定评估标准时最适用。我们报告一例35岁无症状男性病例,其被诊断为右侧运动区附近的小型颅内AVM,采用这种方法进行治疗。由于病灶较小、位置明确、动脉供应位于静脉瘤样扩张近端且瘘管有单一引流静脉,我们采用经静脉途径并在动脉球囊辅助下进行血管内栓塞。该病例说明了TVE方法在将AVM作为潜在的初始治疗选择进行管理时的选择性适应症和技术细节。当患者患有具有所述特定血管构筑学表现的AVM时,使用Onyx或N-丁基氰基丙烯酸酯的TVE可以作为主要治疗方式安全地进行。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b42/7335129/bd45ef9c4c68/AJNS-15-434-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b42/7335129/9f41c9661238/AJNS-15-434-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b42/7335129/7585dbdfec56/AJNS-15-434-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b42/7335129/bd45ef9c4c68/AJNS-15-434-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b42/7335129/9f41c9661238/AJNS-15-434-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b42/7335129/7585dbdfec56/AJNS-15-434-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b42/7335129/bd45ef9c4c68/AJNS-15-434-g003.jpg

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本文引用的文献

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Neuroradiology. 2018 Sep;60(9):971-978. doi: 10.1007/s00234-018-2059-4. Epub 2018 Jul 20.
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Transvenous embolization of brain arteriovenous malformations: a review of techniques, indications, and outcomes.经静脉脑动静脉畸形栓塞术:技术、适应证和结果的综述。
Neurosurg Focus. 2018 Jul;45(1):E13. doi: 10.3171/2018.3.FOCUS18113.
3
Transvenous Curative Embolization of Cerebral Arteriovenous Malformations: A Prospective Cohort Study.
经静脉脑动静脉畸形栓塞治疗:一项前瞻性队列研究。
Neurosurgery. 2018 Nov 1;83(5):957-964. doi: 10.1093/neuros/nyx581.
4
Extending the indications for transvenous approach embolization for superficial brain arteriovenous malformations.扩大经静脉入路栓塞治疗浅表性脑动静脉畸形的适应证。
J Neurointerv Surg. 2017 Nov;9(11):1053-1059. doi: 10.1136/neurintsurg-2017-013113. Epub 2017 Jun 9.
5
Radiosurgery for the management of cerebral arteriovenous malformations.用于治疗脑动静脉畸形的放射外科手术。
Handb Clin Neurol. 2017;143:69-83. doi: 10.1016/B978-0-444-63640-9.00007-2.
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New predictive model for microsurgical outcome of intracranial arteriovenous malformations: study protocol.颅内动静脉畸形显微手术结果的新预测模型:研究方案
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The transvenous pressure cooker technique: A treatment for brain arteriovenous malformations.经静脉压力锅技术:一种治疗脑动静脉畸形的方法。
Interv Neuroradiol. 2017 Apr;23(2):194-199. doi: 10.1177/1591019916682357. Epub 2016 Dec 5.
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Radiosurgery for Cerebral Arteriovenous Malformations in A Randomized Trial of Unruptured Brain Arteriovenous Malformations (ARUBA)-Eligible Patients: A Multicenter Study.随机对照未破裂脑动静脉畸形研究(ARUBA)中适合放射外科治疗的脑动静脉畸形患者:一项多中心研究。
Stroke. 2016 Feb;47(2):342-9. doi: 10.1161/STROKEAHA.115.011400. Epub 2015 Dec 10.
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Neurosurgery. 2016 Mar;78(3):458-65. doi: 10.1227/NEU.0000000000001057.
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